ID A0A0J9E3V2_9RHOB Unreviewed; 1003 AA.
AC A0A0J9E3V2;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Sarcosine oxidase alpha subunit {ECO:0000313|EMBL:KMW57470.1};
DE EC=1.5.3.1 {ECO:0000313|EMBL:KMW57470.1};
GN ORFNames=AIOL_002435 {ECO:0000313|EMBL:KMW57470.1};
OS Candidatus Rhodobacter lobularis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Rhodobacter.
OX NCBI_TaxID=1675527 {ECO:0000313|EMBL:KMW57470.1, ECO:0000313|Proteomes:UP000037178};
RN [1] {ECO:0000313|EMBL:KMW57470.1, ECO:0000313|Proteomes:UP000037178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IGS {ECO:0000313|EMBL:KMW57470.1};
RA Jourda C., Santini S., Claverie J.-M.;
RT "Draft genome sequence of an Alphaproteobacteria species associated to the
RT Mediterranean sponge Oscarella lobularis.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMW57470.1}.
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DR EMBL; LFTY01000002; KMW57470.1; -; Genomic_DNA.
DR RefSeq; WP_049643196.1; NZ_LFTY01000002.1.
DR AlphaFoldDB; A0A0J9E3V2; -.
DR STRING; 1675527.AIOL_002435; -.
DR PATRIC; fig|1675527.3.peg.2556; -.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000037178; Unassembled WGS sequence.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:UniProtKB-EC.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR006277; Sarcosine_oxidase_asu.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR01372; soxA; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PIRSF; PIRSF037980; SoxA; 1.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:KMW57470.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000037178}.
FT DOMAIN 170..421
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 521..603
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 619..884
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 910..995
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 1003 AA; 109292 MW; 130766C7CC5B2C9E CRC64;
MSTRLTQGGR LIDRAQRLDF TFNGKRLSGH PGDTLASALL ANGQMLMGRS FKYHRPRGPV
ASGPEEPNAL MQIGKEGRFE PNQRATVQEL FDGLEAASQN HWPSLDHDVG VVNNYMSRFL
TAGFYYKTFI HPRAAWKHVF EPIIRKAAGL GAAPQDRDED TYEHYHTHVD VLVVGGGIAG
LAAARQAGAA GAQVLLVEQG AEWGGRAQVD GAEIDGMSAE DWIKKTLQEL EAMENVRLRI
RCMGSGVYDH GYCLAYERLT DHLTEKDGPR HRLWKIRARQ VVTATGAIER PLSFACNDVP
GVMLAGAVRD YVVNYGVSPG DRTVVVTNND DAYRTVIALK NAGLEVPCVI DARQTPASPL
IDQVRDMGVR IEFGRGIGKV KGGKRVEGIT IGIQGGEGAV LEEIKCDAVA MSGGWSPVVH
LWSHCGGKLV WDDAQAHFRP DPDRAPTGAD GAGFVRCAGM ANGSMSTAEV LADADAQGRA
AAMAAGHKKR KKAAPKAATE TPAAIEPVWV MPQGAPSELR QKMWLDFQND VKVSDVQLAA
REGFESVEHT KRYTTLGMAT DQGKLSNING LAVLSDSLGA AIPEVGTTTF RPPYTPISMG
AIGGEARGDV FQPLRRSPMH DWHDANGAFW EPVGHWRRPY CYQRPGESVE EAVNREVLNT
RKRLGLLDAS TLGKLIVKGP DAGKFLDMMY TNMMSTLKVG RCRYGLMCSE NGFLSDDGVV
ARIDEDTYLC HTTSGGADRI HAHMEEWLQT EWWDWQVYVV NATEQYAQVA VVGPDARKVL
ETIGGMDVSA EALPFMAWAD GEIGGFKVRV YRISFSGELS YEIAVDAHQG AAFWDMLMEA
GAAYGAMPYG TEALHIMRAE KGFIMIGDET DGTVIPQDLG LHWAVSKKKD DFIGKRAQER
SFMVDPERWQ LVGLETVDGG VLPDGAYAVA EGANANGQRN VQGRVTSTYH SPTLERGIAM
GLVLHGPERM GEVLNFPGVD GTEQQARIVS PVFYDPEGEK QNV
//
