ID A0A0J9UWT7_FUSO4 Unreviewed; 710 AA.
AC A0A0J9UWT7;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Salicylate hydroxylase {ECO:0000313|EMBL:KNB03021.1};
GN ORFNames=FOXG_05631 {ECO:0000313|EMBL:KNB03021.1};
OS Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935
OS / NRRL 34936) (Fusarium vascular wilt of tomato).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=426428 {ECO:0000313|EMBL:KNB03021.1, ECO:0000313|Proteomes:UP000009097};
RN [1] {ECO:0000313|EMBL:KNB03021.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=4287 {ECO:0000313|EMBL:KNB03021.1};
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Ma L.-J., Jaffe D.,
RA Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.,
RA Brockman W., MacCallum I.A., Young S., LaButti K., DeCaprio D.,
RA Crawford M., Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C.,
RA Larson L., White J., O'Leary S., Kodira C., Zeng Q., Yandava C.,
RA Alvarado L., Kistler C., Shim W.-B., Kang S., Woloshuk C.;
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KNB03021.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4287 {ECO:0000313|EMBL:KNB03021.1};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
CC -!- SIMILARITY: Belongs to the paxM FAD-dependent monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00007992}.
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DR EMBL; DS231701; KNB03021.1; -; Genomic_DNA.
DR RefSeq; XP_018241066.1; XM_018384044.1.
DR AlphaFoldDB; A0A0J9UWT7; -.
DR GeneID; 28947594; -.
DR KEGG; fox:FOXG_05631; -.
DR VEuPathDB; FungiDB:FOXG_05631; -.
DR OrthoDB; 1113861at2759; -.
DR Proteomes; UP000009097; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.400.10; Acetoacetate decarboxylase-like; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR010451; Acetoacetate_decarboxylase.
DR InterPro; IPR023375; ADC_dom_sf.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR13789; MONOOXYGENASE; 1.
DR PANTHER; PTHR13789:SF261; SALICYLATE HYDROXYLASE_MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13860)-RELATED; 1.
DR Pfam; PF06314; ADC; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF160104; Acetoacetate decarboxylase-like; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000009097};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 26..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..386
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 710 AA; 79379 MW; 4BDBBF927447EDA9 CRC64;
MDHIMKPNGV SHAVINGHTA AAKSDGLNIV VIGAGIGGLT AAIFLRRQGH RVTLLEQSRF
ANEVGAAMHL APNANGILRR LGIFAETIGA NVFERIKEFN AANEVIRDAE LTEANKIWQH
PWHLVHRVRL HQELKRLATS PEGPGIPAVL RTSSRVVDVD TETATVFLQD GGKVQGDLVI
GADGVHSRSR QKIVGKDWQA YSSGKSAFRF LVPRQDALDD PETAHFAQHN GQLIIWYAAD
RRIVMYPCDD NKMFNFVCIH PREESDPGSK EDWNNETSMS VLLNVYKDFD PALLKLLSKA
SPESLKAWEL LDMDVLPTWT DKRLTLLGDA AHPFLPHQGQ GAGVAIEDAA SLAVVLPLGT
SPEEVPERLR LYQDFRYDRA NRIQEFSRQA GKDKPDKDFD MMAYSNFNFG HDEWDHSTNR
FRNWDWARKP HLYWRMPISF GPFPGPRQTF TGEARNATDS TFTTASIKFK TSRTLLQNLF
PSTSFRFKSP GTVAYASFSQ TTLNKMEWLG GSGYRHIGLY IHGVQYVQKD GTVRDGTFLP
ILWENLTDPI VSGREELGMP KLYCSIDVWR RTNSYRIQTG WQGVNFGSFT LEGLHETDSG
SSKGTIGGED DEGIFAYKYI PKVGDRGKAD VEHATFVPHS EESKVVPSQV LRVFTADKAS
FEFDPHDWEA LPTLHHVVSR LAEVPVYEIL GGKVVEGVGV PDVSSARRID
//
