ID A0A0J9VLF8_FUSO4 Unreviewed; 559 AA.
AC A0A0J9VLF8;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Aldehyde dehydrogenase (NAD+) {ECO:0000313|EMBL:KNB11601.1};
GN ORFNames=FOXG_11443 {ECO:0000313|EMBL:KNB11601.1};
OS Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935
OS / NRRL 34936) (Fusarium vascular wilt of tomato).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=426428 {ECO:0000313|EMBL:KNB11601.1, ECO:0000313|Proteomes:UP000009097};
RN [1] {ECO:0000313|EMBL:KNB11601.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=4287 {ECO:0000313|EMBL:KNB11601.1};
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Ma L.-J., Jaffe D.,
RA Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.,
RA Brockman W., MacCallum I.A., Young S., LaButti K., DeCaprio D.,
RA Crawford M., Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C.,
RA Larson L., White J., O'Leary S., Kodira C., Zeng Q., Yandava C.,
RA Alvarado L., Kistler C., Shim W.-B., Kang S., Woloshuk C.;
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KNB11601.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4287 {ECO:0000313|EMBL:KNB11601.1};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
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DR EMBL; DS231710; KNB11601.1; -; Genomic_DNA.
DR RefSeq; XP_018249646.1; XM_018391064.1.
DR AlphaFoldDB; A0A0J9VLF8; -.
DR GeneID; 28952846; -.
DR KEGG; fox:FOXG_11443; -.
DR VEuPathDB; FungiDB:FOXG_11443; -.
DR OrthoDB; 216092at2759; -.
DR Proteomes; UP000009097; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR43720; 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43720:SF3; ALDEHYDE DEHYDROGENASE ALDH (AFU_ORTHOLOGUE AFUA_8G02310)-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000009097}.
FT DOMAIN 88..551
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 325
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 559 AA; 60829 MW; 3F91F3892A07100A CRC64;
MSLRSYKKMG AALASRLPLV GFCRSVYPSL SRPSTQSLYR LSLSPLGRSI TTTQKRFSNM
SDLFVNLEAP NGVKYTQPTG LFINNEFVPG SSKQKITSID PATEKEIATV HAASADDVDK
AVKAAHAAFH APSWKKMPPP QRGALMNKLA DYIEERTQMF ATSEAWDNGK IYADAEGGDV
VEVINTIRYY AGWADKITGQ TITANPNKLA YTLRQPLGVV AQIIPWNYPL AMAAWKIGPA
LACGNTIVMK AAEQTPLSIL LLGQAFKDVG FPPGVFNALN GYGGEAGPPL VQHPLVEKVA
FTGSTATGAK IMEMASKTLK NITLETGGKS PLLVFSDCDL DEAVKWSHMG IMSNQGQICT
ATSRLLVQDK VYDEFVQRFI ETTKTVSKVG HQWDSETYQG PQVSRQQYDR ILEYIKIGKS
EGATLLAGGQ PVDASKKGFF VQPTVFGDVH HQMRVFREEI FGPVVVITKF SSEEEALKLA
NDSTYGLGAA VFTKDVERAH RVAAEIEAGM VWINSTQDSE PYIPFGGVKQ SGIGRELGEA
GLEAYSNTKS VHVNLGSRL
//
