ID   A0A0J9XCI4_GEOCN        Unreviewed;      2332 AA.
AC   A0A0J9XCI4;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Similar to Saccharomyces cerevisiae YOL081W IRA2 GTPase-activating protein that negatively regulates RAS by converting it from the GTP-to the GDP-bound inactive form,partial (Partial) {ECO:0000313|EMBL:CDO54558.1};
DE   Flags: Fragment;
GN   ORFNames=BN980_GECA08s01005g {ECO:0000313|EMBL:CDO54558.1};
OS   Geotrichum candidum (Oospora lactis) (Dipodascus geotrichum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Geotrichum.
OX   NCBI_TaxID=1173061 {ECO:0000313|EMBL:CDO54558.1, ECO:0000313|Proteomes:UP000242525};
RN   [1] {ECO:0000313|EMBL:CDO54558.1, ECO:0000313|Proteomes:UP000242525}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 918 {ECO:0000313|EMBL:CDO54558.1,
RC   ECO:0000313|Proteomes:UP000242525};
RA   Casaregola S.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CCBN010000008; CDO54558.1; -; Genomic_DNA.
DR   STRING; 1173061.A0A0J9XCI4; -.
DR   OrthoDB; 1356198at2759; -.
DR   Proteomes; UP000242525; Unassembled WGS sequence.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR   Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR039360; Ras_GTPase.
DR   InterPro; IPR023152; RasGAP_CS.
DR   InterPro; IPR001936; RasGAP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   PANTHER; PTHR10194:SF150; INHIBITORY REGULATOR PROTEIN IRA1-RELATED; 1.
DR   PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR   Pfam; PF00616; RasGAP; 2.
DR   SMART; SM00323; RasGAP; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR   PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT   DOMAIN          856..1052
FT                   /note="Ras-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50018"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CDO54558.1"
SQ   SEQUENCE   2332 AA;  263571 MW;  2C7F941A2B839950 CRC64;
     TSKKQNFFSA LNTMISTSAL ESQSNELLIA ATKHIIKAGS LLQALTPSSP IVSYSKSLYP
     VLLSQLFALP SKTSHIINVN LFQCTFVTSF SVLNTERLLK DLFPIIASKD DFMFCIPNIL
     QGLIILRQVS VFTEYFDTIM NSIAPTLRSV LTDTTVQLRF FESQSNFTAE LSRSNIYRNY
     ADIICKSYTI FSYNYFYFIK DYTRYPNLKD DVVFMSLVQA TLSSNSVVER KALDFILLFL
     DKERLLNLAT HEINVENPEK ILLTYLQCGS MAELHANRLI ELDSNGENSI SHLTLIKHVL
     EARCTIIEAS KLDQVCNRDP TRLEPREQRK SVSSTIETAM YITLCSINTT VCTLSLEILK
     LLVQEAVLIE DLTNMSESVW SIMPNFDMHS EFASSTYVFT GSIAIQKRLY QFLQHIEMAT
     PAIIAAWNCL ILRWRNLTKS IISSTSVDRD IFKQWKSYAG FLCSVLSPHL VQSEQDRPRS
     VQGPNPLSPQ QSYADISVNE YLSASSKEFL SEMISLLTFV KSPFLRETAR DVLSRDTSHF
     SYHHIFKSLE VDIKSRLQDT SSTLFEQDFL LLEQSVQLLR SIATSNEEST NRVSVDMGAL
     ALTIVKCLDS LPVDERVIRL RIQYCSLFEF IAGHEHSLNM KHDISIRNEI TSIFAVWLEK
     NLSSNFADDT LSTYSGSTSS KSIRKSSFHD SRERLEKNSI CAIIKSYTVI LKSLRLEPLE
     AIHEIHILEA KAQKFGTLFT LFLRILEKCR LEEDHAPGSL NLGERLSTVK NQTITCASHL
     LNANMDVGLK FVLPLGLKND NFIRVSFITI LDNLLSSETN EHSGFSDTQP YQDLAEFIVK
     NISVTLSLCD ICPATEVDDF SKALLEIFEA KGKCLDLVNT LVTREVAKAD APLEILRRNC
     VATKILSLFA QNKGFEYLKS TLEPFLREMI ENPELYVFEL NPDKISDGES LDSNFNKCER
     TLKKLIGSLQ RSVDDVPIEL KHICNTIAVT VAPKFSGTKD NSITAISAFF FLRFICPALV
     TPEVNNLLET APPKPVRRTL LSLAKIIQNM AFGSTSFVKL SIFKHHPGTY SPNSALIMQF
     LKNLSILSTE ETEKSPSPSQ VSNCEQKDID VIHRFLYHHW EDVNHRMILD MRLNSKVTPN
     GSRSSFIDPR RSTISSEVEE NELKLNHKLT TLVRNLGRPR SIKQNAPLIT KDAFSLKLNN
     APRLQELLTR NAHRDMTPII EREVINDGIT KDGMPLIVMN TRNYDKTNID TELVLCRFFH
     VASKMWKQKY GIFVDCTGYS PANGFPMSAR LISDMLITED MIRNIHGISF LNVSSDYLPH
     LKSLVKHYCS GIFLNPSRIQ YKFFTTTDIP TLFNERVLNL TPKTLGIVRD VRIIYNNVYR
     YNPTRNDVTQ MTLKLGNEYI QLRSQEAFHY VKTAPGYTND IYHLSEIVNV YSSNTNSHPD
     EFTIQLSSFE NRKIILHCSR RHDIIRALQN AMANLISTGA KNSHLVMSPE RSFSALLNIA
     FSGLCSENSS TQGASYNLLA SIQKRFSLKL GVTLEGGKGL KLPTNVFSLV QKISQAVATA
     RPEVTFEMFR YLFEAFEITS PDRRQGILIY SIPWVKNLVS VVTKGGYNKQ VEKSIALNTR
     KFLEISLTGD RDYMFLLHSV WPLILSEIKF VDIVLDEIIF LVAENEIQLG NQMDDIVSVL
     ASNPTLDVCK VVMSRLKNIT LVHKGTGTPL VKHSRWNEMV IHLTLLSALL FENPECVEEM
     FAELSLSVLL QISTGPYLHR MTVFNLVINM LQSFLYTDKC DEEKRKHLHT IWDELTGSKG
     SMIFGISEEM KSVDYDYPVT SLIFQIEACT TILTDMANSI VPHRMSSEYR PFLIQKLIKL
     GSQQYSSFQS RSILILGCVA RVDVSDRDVT QILEFAAVAI TNPGDPATKE ELLTCLTFCI
     SRVTDGLRLD SKYLPKLFWL AIAILSTRNM GIFNYALHLL QTTLKTLDEY GAFKNLPTIG
     HYFMGVKEAF KNEWMLLEKE THTVFSTESF DLQLCAVLLP GLESSITRAA TLSVFESLLS
     VSARNSTQIR DSDTFDSNSL RDRTNSTTSI AQQHSNALAA AAASTTTGRY ATNTVDEEVV
     TVSSSSMHFS TASATKFPSY MPYLIVLYLG SRTSAELRDY LWIAGFPDER IDNEIPVQIK
     NYLVSDKPEA LISLYLCTLI FRSVSGNEEN MDSRVLACLR HVGSMNSDVF FKVYFTARPK
     VQDIMDSGPS LTLLKAALEV AKSALSHMDD IGKKHYYLKE MDIILIEHGL KSLTSEYKCD
     QPKTSQQVLI QQQLKGRKFH EIGTLFTKII ALHTAAEDLA SPSSVITEGF TF
//