ID A0A0J9XI75_GEOCN Unreviewed; 1227 AA.
AC A0A0J9XI75;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Similar to Saccharomyces cerevisiae YLR398C SKI2 Ski complex component and putative RNA helicase {ECO:0000313|EMBL:CDO57126.1};
GN ORFNames=BN980_GECA19s00120g {ECO:0000313|EMBL:CDO57126.1};
OS Geotrichum candidum (Oospora lactis) (Dipodascus geotrichum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Dipodascaceae; Geotrichum.
OX NCBI_TaxID=1173061 {ECO:0000313|EMBL:CDO57126.1, ECO:0000313|Proteomes:UP000242525};
RN [1] {ECO:0000313|EMBL:CDO57126.1, ECO:0000313|Proteomes:UP000242525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLIB 918 {ECO:0000313|EMBL:CDO57126.1,
RC ECO:0000313|Proteomes:UP000242525};
RA Casaregola S.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. SKI2 subfamily.
CC {ECO:0000256|ARBA:ARBA00010140}.
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DR EMBL; CCBN010000019; CDO57126.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J9XI75; -.
DR STRING; 1173061.A0A0J9XI75; -.
DR OrthoDB; 1352at2759; -.
DR Proteomes; UP000242525; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR Gene3D; 1.10.3380.30; -; 2.
DR Gene3D; 2.30.30.1160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR048392; MTR4-like_stalk.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016438; SKI2-like.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR InterPro; IPR048727; Ski2_beta-barrel.
DR InterPro; IPR040801; Ski2_N.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF21408; MTR4-like_stalk; 1.
DR Pfam; PF21409; Ski2_beta-barrel; 1.
DR Pfam; PF17911; Ski2_N; 1.
DR PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:CDO57126.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 290..446
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 578..755
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 490..542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 527..542
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1227 AA; 138081 MW; 7752213D5337EC48 CRC64;
MSIADIIDSI RVNISSNDPA VDFETFNTKV DETSDEYIQS TFLTPSTHFS NQWLNNLQEL
PPVDPLSQAT ELFTLPDTRS NTGVRFKRAG LEGRVVAYEE YSITSDALSK TAKNSLSINR
KTSSKLDFIQ GRAGFMPFTP GGVELPETPV NKQALHRDDN GLYDVPPGFP RGFIEEETAK
EVNELIYDED EELTDSEDDQ SQELTNQIQN FAFSQSDENS KYSSKELDNL LPDEMTFGRV
QASDAEALPK AKEWAHVVDV NKAIPNFSEL VPKPAKVFPF ELDTFQKEAV YHLEQGDSVF
VAAHTSAGKT VVAEYAIAMA TRNMTKAIYT SPIKALSNQK FRDFKEVFDD VGILTGDVQI
NSEANCLIMT TEILRSMLYR GADVIRDVEF VIFDEVHYVN NQDRGVVWEE AIIMLPEHVK
LILLSATVPN TYEFANWVGR TKQRDIYVIS TPKRPVPLEH YLWAADAPYK IVDEHKKFLE
PGYAQASNAV APKPNVASNG RGGGRGGSDA GRGRGGARGR GGRGANRGGG NTQSYVPSYN
GRQSNNNTFG KRAFLKLCSH LKAKNLLPAV IFVFSQKLCT QYAVSLSSID YSTAKEKSEI
HMFIDKAVSR LKKEDRNLPQ IQMIRELLGR GIGIHHGGLL PIVKETIEIL FAKSLVKVLF
ATETFAMGLN LPTRTVIFGS IRKHDGHSLR TLLPGEYTQM AGRAGRRGLD PTGTVMIMTS
EPFPTASSLR ELILGNPTKL HSQFRLTYNM ILNLLRIEAL RVEEMIKRSF SENANQVMLP
EHQKTVKLNE QALSQLKRPP CMICDVDMDK VLPLIVRERE LHSSIMDDIS RTTIGRSMFT
PGRVVVFKDE RNTRAMGIVT KFDDRKRLNL LTFTKLTAKP DKKGDIPFYT GIEGFGKKHL
SNYFSINLPF GVSIVPVSSV EVISTVRLNM DIPSLIRGHP EEVKKSVNYL KGVLNHQSEL
KELFIRGIRS PAILSKIHER DRLMLEIKQA KCIQCPTFVD SFLLDYKVFT IKQQIENLQQ
LMSSENMDLL PDYEQRIEVL KELNYIDEEQ NVQLKGRVAC EINTGFELII TELVLDNFLA
SYEPEEIVAL LSVFLFPGNT KVEPTTITPQ LDVGKAKIVE VVTKVLDVFE KHKVLVTQEE
VEFLEKNRFG LMEVIYEWGR GMNFSEIMEL TDVAEGTIVR VISRMDEVCR QVMAAARIIG
DSTLYDKMEA AQEKIKRDIV FCASLYL
//
