ID A0A0J9XTQ3_BRUMA Unreviewed; 669 AA.
AC A0A0J9XTQ3;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 03-MAY-2023, entry version 42.
DE SubName: Full=BMA-UNC-115, isoform b {ECO:0000313|EMBL:CDP94970.1};
GN Name=Bma-unc-115 {ECO:0000313|EMBL:CDP94970.1};
GN ORFNames=Bm3213 {ECO:0000313|WormBase:Bm3213b}, BM_Bm3213
GN {ECO:0000313|EMBL:CDP94970.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CDP94970.1};
RN [1] {ECO:0000313|EMBL:CDP94970.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP94970.1};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CDP94970.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP94970.1};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LN856931; CDP94970.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J9XTQ3; -.
DR WormBase; Bm3213b; BM46304; WBGene00223474; -.
DR OMA; PSCEHAR; -.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR CDD; cd09327; LIM1_abLIM; 1.
DR CDD; cd09329; LIM3_abLIM; 1.
DR CDD; cd09330; LIM4_abLIM; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 3.
DR Gene3D; 1.10.950.10; Villin headpiece domain; 1.
DR InterPro; IPR003128; Villin_headpiece.
DR InterPro; IPR036886; Villin_headpiece_dom_sf.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24213; ACTIN-BINDING LIM PROTEIN; 1.
DR PANTHER; PTHR24213:SF9; UNCOORDINATED 115A, ISOFORM B-RELATED; 1.
DR Pfam; PF00412; LIM; 3.
DR Pfam; PF02209; VHP; 1.
DR SMART; SM00132; LIM; 3.
DR SMART; SM00153; VHP; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 3.
DR SUPFAM; SSF47050; VHP, Villin headpiece domain; 1.
DR PROSITE; PS51089; HP; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 2.
DR PROSITE; PS50023; LIM_DOMAIN_2; 2.
PE 4: Predicted;
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 39..100
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 146..205
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 604..669
FT /note="HP"
FT /evidence="ECO:0000259|PROSITE:PS51089"
SQ SEQUENCE 669 AA; 75645 MW; E514964A02341755 CRC64;
MPKSPLSSTS SSTAQLSYYQ KSFCPVGEWL GCLCVAMGKK CYVCRKKCIG EILKADGEKY
IHISCFKCAK CSRSLRETGY YTGSEGQFLC AEDFRALSVP LKVKAEQQNL KHADETSLSP
ASPIIPPGQP SPPLISPADI RQVSAAGCAS CGQPLQSGQV LLALGEQWHV WCFKCSECTT
ILQGEYMTHD GKPLCIRDYN TKYGVRCYEC DKYIAGKVLQ AGGYKFHPTC ARCSRCGERF
GDGEEMYMQG DEIWHPGCEQ TKVTESIALT GLLNDAREEP KYHSHFGQHL TYMYLLPEAE
QTYLKQPIPP HPPQLAQFHT PQGPIKIRKS RLSMLKTGMQ RLTEDLEKSA PRPRSPHMDN
EEPIEMAHYP AGHAPEPGIV PPIERADFPA PPYPYALDDV KRHLSWSSVE NDDDDDEDDY
EESNRINDEK LRRAVEQLDT YDKDSSIARV IKQNLEEVHK KQRLPLHWDP RNASRTPSAK
KMPHLRFRYD TPVNASPSRH VNRPKPWVYW QRQTDKAATT SIPFFHIPRA CVEMTGRSAT
LPDGYHYGQN VSLDVLNTTI SSHFSDQLLG RSGTLPGDYR TCTTNGAGTG GSRGTLRSSL
PDMSKPAKIY PLNVLQTSNK KLPDDVDRAH LERHLNRNQF EETFNMSPIE FYKLPEWKRI
NLKRKAKLF
//
