ID A0A0J9XXT5_BRUMA Unreviewed; 939 AA.
AC A0A0J9XXT5;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=14-3-3 domain-containing protein {ECO:0000313|WBParaSite:Bm10299b.1};
DE SubName: Full=Bm10299, isoform b {ECO:0000313|EMBL:CDP97515.1};
GN ORFNames=Bm10299 {ECO:0000313|EMBL:CDP97515.1,
GN ECO:0000313|WBParaSite:Bm10299b.1, ECO:0000313|WormBase:Bm10299b},
GN BM_Bm10299 {ECO:0000313|EMBL:CDP97515.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CDP97515.1};
RN [1] {ECO:0000313|EMBL:CDP97515.1, ECO:0000313|Proteomes:UP000006672}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP97515.1,
RC ECO:0000313|Proteomes:UP000006672};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CDP97515.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP97515.1};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:Bm10299b.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2019) to UniProtKB.
CC -!- SIMILARITY: Belongs to the 14-3-3 family.
CC {ECO:0000256|ARBA:ARBA00006141}.
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DR EMBL; LN856986; CDP97515.1; -; Genomic_DNA.
DR EnsemblMetazoa; Bm10299b.1; Bm10299b.1; WBGene00230560.
DR WBParaSite; Bm10299b.1; Bm10299b.1; WBGene00230560.
DR WormBase; Bm10299b; BM31521; WBGene00230560; -.
DR Proteomes; UP000006672; Unassembled WGS sequence.
DR CDD; cd08774; 14-3-3; 1.
DR Gene3D; 1.20.190.20; 14-3-3 domain; 1.
DR InterPro; IPR000308; 14-3-3.
DR InterPro; IPR036815; 14-3-3_dom_sf.
DR InterPro; IPR023410; 14-3-3_domain.
DR PANTHER; PTHR18860; 14-3-3 PROTEIN; 1.
DR PANTHER; PTHR18860:SF160; 14-3-3 PROTEIN ZETA; 1.
DR Pfam; PF00244; 14-3-3; 1.
DR PRINTS; PR00305; 1433ZETA.
DR SMART; SM00101; 14_3_3; 1.
DR SUPFAM; SSF48445; 14-3-3 protein; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006672}.
FT DOMAIN 10..247
FT /note="14-3-3"
FT /evidence="ECO:0000259|SMART:SM00101"
FT REGION 442..501
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 643..677
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 742..772
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 792..816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..460
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 643..668
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 939 AA; 107377 MW; 2F0EFE30EB2CAA1A CRC64;
MNEGAQVVDR YNLMLRIRIA NALSLFDDAR QNFQILIGNY GKELTKEERN FFAVFYKSLL
DKFRKEYNMY MDLQREIPRR EILKHRILRD NMYRARYEVV TICKEVIDMI DHGILDTKNI
ELKIYFIKLR ADYFRYWSGV VSEEQFFGVR KRAEDSYQLA LELADKKLKK YHPIRLALML
NMSIHYYAVP CERIKALQLS MQAVTEGKDH TKNDADIREV VDLLRDNLDA WMADLGPKEV
HELEILEGAR KWHGKGAAVP SAHLRRRLSG EESPKYNTPV LTRQRYFTIP QPYVRYNKFD
DIYVCNYVPL KRNPSVFYEP LFEPETIYPA SHKKKVPLTV TESVITKSKS TAAELKKTQT
KLQVTTSVAT TSSTILAAIG LLPSTAADQE TNYTEVPENI HLSTSHIKPV ESTVLLEDAS
HEKHVSLPDP FEGILQPILS FSSTQSSSTT SSSTTTSQSS LDEHNEDDNG NPEQRENRPS
IWTSAPRDIP QHRLTPTTID PISRLTKRLR SFESRMLSIK RSQLRLEQLS AEQGQQSNEE
NDSPLELRWT AGVANEEPQT TSNIITAATT SPFHVPQQDV TSEISVPSYT QITNEFITVE
NLQPKLQNIP TDNRDAELQQ RSTISSNQPD MLTFLPKIKS FASHQQRQNI TETEPKDSST
SSGSFVFPES APPTPPPQVI FTPFGPKIVG NFSPTSSLEG AVAAVSPPLL ENKKRSRVVT
FSEKCTYWPL QSAVETGNWN RRFSRQRTRR QRSSIRPPPL RSPTPEIEEQ VPCLPRSSQE
IAVVPQQNLS PHQTSFNRQQ FHRKGQALKG RSRRKLSQRK LLRRSFSAPR EGATWPISSL
TREPPYFIYM VLRRASAASG QAFGRRFLSA HSSAEDLYDE AAEKAFPDPW APRGARTMHN
TFPITPWYPN EKPRVPWIRH QWPYRGAGNE ENVSSGMQD
//
