ID A0A0J9XYG7_BRUMA Unreviewed; 744 AA.
AC A0A0J9XYG7;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Bm10391 {ECO:0000313|EMBL:CDP97898.1};
GN ORFNames=Bm10391 {ECO:0000313|EMBL:CDP97898.1,
GN ECO:0000313|WormBase:Bm10391}, BM_Bm10391
GN {ECO:0000313|EMBL:CDP97898.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CDP97898.1};
RN [1] {ECO:0000313|EMBL:CDP97898.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP97898.1};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CDP97898.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP97898.1};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LN856992; CDP97898.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J9XYG7; -.
DR WormBase; Bm10391; BM44839; WBGene00230652; -.
DR OMA; HICYKER; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR045095; ACDP.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR PANTHER; PTHR12064; METAL TRANSPORTER CNNM; 1.
DR PANTHER; PTHR12064:SF59; UNEXTENDED PROTEIN; 1.
DR Pfam; PF01595; CNNM; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|PROSITE-ProRule:PRU01193, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|PROSITE-ProRule:PRU01193,
KW ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|PROSITE-ProRule:PRU01193,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..744
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007412392"
FT TRANSMEM 175..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 171..351
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
SQ SEQUENCE 744 AA; 85009 MW; 064944C07C3BBBA7 CRC64;
MAAIIIAFTI ISIAFLKLGI KGSNIDSLPK HQEIEIEFVT YEVRPYVSGI RVISMPSKNS
LISYSESGAT IIYPDSRARI VMFGYHLDKI GIISLTTGNC FNSVVNISRP EFLIQTVKRL
DFVAYFAKSD EPYHICYKER MSRKESREEE DMIMMDESRN SIVTEAPARI YYLPIYLQIS
IIFMLFCLSA LFSGLNLGLM ALSPQELMLI QKCGSKMERK YAEIILPVRQ SGNYLLCTIL
IMNVVVNAAI SILFEDMTSG MIAFIVSSVG IVVIGEIIPQ SICVKKGLAV GAYTIWLTRT
FMILTFPFSY PISKILDVFL GEDTPVYDRC KLINLMKMTA CEENQELAAD LKIAVGAMEI
SEKTVGDVLT KIEAYPAMFH TYKTLRKYFK FKSHQTFMQQ DVFMLSEDTI MGTATVLEIL
RHGYSRIPIY ADDDRNNIKA LLMVKDLALI DPRDNLTVKT ICEFHHYPLR FGNYHLAIVE
SVQSMYDRKI SQQTKNLLGI VTLEDIVEEI LQAEIIDESD SVTDNMYRSK RKRVKEPCFT
KFLTNEEYGK KLSLHMEQMT IHFLQQHHVI FSDEYVDRQV LSHLLKSNIR QIDMSHSPRI
IGYSAKQRET IPIYCMNTPA FRFVVVLEGR AIVKLRNMEF EIGPWTSFGK EILDQIDELI
NGNLITDESD LLVHSDSKSE LINSIQFNPD FDLFVTDFCR FLHLTVSTYL NAIKATKIAR
MARNEQDSIK SILKPSLCPA TQSL
//
