ID A0A0J9Y0G4_BRUMA Unreviewed; 185 AA.
AC A0A0J9Y0G4;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=BMA-RHEB-1 {ECO:0000313|EMBL:CDP99024.2, ECO:0000313|WBParaSite:Bm4347.1};
GN Name=bma-rheb-1 {ECO:0000313|WormBase:Bm4347};
GN Synonyms=Bma-rheb-1 {ECO:0000313|EMBL:CDP99024.2,
GN ECO:0000313|WBParaSite:Bm4347.1};
GN ORFNames=Bm4347 {ECO:0000313|WormBase:Bm4347}, BM_Bm4347
GN {ECO:0000313|EMBL:CDP99024.2};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CDP99024.2};
RN [1] {ECO:0000313|EMBL:CDP99024.2, ECO:0000313|Proteomes:UP000006672}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP99024.2,
RC ECO:0000313|Proteomes:UP000006672};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CDP99024.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDP99024.2};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:Bm4347.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2019) to UniProtKB.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rheb family.
CC {ECO:0000256|ARBA:ARBA00037969}.
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DR EMBL; LN857006; CDP99024.2; -; Genomic_DNA.
DR RefSeq; XP_001900388.1; XM_001900353.1.
DR STRING; 6279.A0A0J9Y0G4; -.
DR EnsemblMetazoa; Bm4347.1; Bm4347.1; WBGene00224608.
DR GeneID; 6103809; -.
DR KEGG; bmy:BM_BM4347; -.
DR WBParaSite; Bm4347.1; Bm4347.1; WBGene00224608.
DR CTD; 6103809; -.
DR WormBase; Bm4347; BM38490; WBGene00224608; Bma-rheb-1.
DR OrthoDB; 8685at2759; -.
DR Proteomes; UP000006672; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR InterPro; IPR020849; Small_GTPase_Ras-type.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR24070:SF226; GTP-BINDING PROTEIN RHEB HOMOLOG; 1.
DR PANTHER; PTHR24070; RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006672}.
SQ SEQUENCE 185 AA; 20839 MW; A458922E5FA0C22E CRC64;
MANAIQRKIA VMGYPCVGKS SITLRFVYGN FPDAYDTTIE DIYTKSYKFN GKQFALQITD
TAGQQEFSLF PRSCAIDIDG YILVYAIDDR KSFEIVQSIY DKIMENLGDK NIPIVVVGNK
LDLHFNARHV STEEGRQLAV AWNAAFLETS AKDNTSVEQI FDCLLREIEI ANGNMKRNRN
GCVLS
//
