ID A0A0J9Y5M2_BRUMA Unreviewed; 520 AA.
AC A0A0J9Y5M2;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=BMA-SNX-27, isoform a {ECO:0000313|EMBL:CDQ02892.2, ECO:0000313|WBParaSite:Bm3582a.1};
GN Name=bma-snx-27 {ECO:0000313|WormBase:Bm3582a};
GN Synonyms=Bma-snx-27 {ECO:0000313|EMBL:CDQ02892.2,
GN ECO:0000313|WBParaSite:Bm3582a.1};
GN ORFNames=Bm3582 {ECO:0000313|WormBase:Bm3582a}, BM_Bm3582
GN {ECO:0000313|EMBL:CDQ02892.2};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CDQ02892.2};
RN [1] {ECO:0000313|EMBL:CDQ02892.2, ECO:0000313|Proteomes:UP000006672}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDQ02892.2,
RC ECO:0000313|Proteomes:UP000006672};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CDQ02892.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CDQ02892.2};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:Bm3582a.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2019) to UniProtKB.
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DR EMBL; LN857024; CDQ02892.2; -; Genomic_DNA.
DR STRING; 6279.A0A0J9Y5M2; -.
DR EnsemblMetazoa; Bm3582a.1; Bm3582a.1; WBGene00223843.
DR WBParaSite; Bm3582a.1; Bm3582a.1; WBGene00223843.
DR WormBase; Bm3582a; BM38484; WBGene00223843; Bma-snx-27.
DR OrthoDB; 2874169at2759; -.
DR Proteomes; UP000006672; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd06886; PX_SNX27; 1.
DR Gene3D; 1.20.80.60; -; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR037831; SNX17/27/31-like.
DR InterPro; IPR037833; SNX27_PX.
DR PANTHER; PTHR12431; SORTING NEXIN 17 AND 27; 1.
DR PANTHER; PTHR12431:SF19; SORTING NEXIN-27; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF00788; RA; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS50200; RA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000006672};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
FT DOMAIN 27..120
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 147..255
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT DOMAIN 259..347
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
SQ SEQUENCE 520 AA; 58977 MW; B4E76D884BEA31F9 CRC64;
MMGDESDSSE DCFMVPVRHN FNPKPHLVTV VKSDTGFGFN VKGQVSEGGQ LRSINGELYA
PLQHVSAVLR GGAAAKAGLL KGDRILQVNG VDVEGATHKQ VVELIKDGGD KLSLVVISVD
AVDAERFENG LTEETCASCR YDYSEKRSLP ITIPSYQTIT ANGERFIAYN VHMAGRHLGS
RRYSEFVQLH NLLKHEFIDF DFPKLPSKWP FSLSEQQLDA RRRGLESYLE KICAIRVIAD
SDIMQEFLME DSLSECAIAD VHIRILLPDG NSLLLNIKRH CTAIELYMAT QKRLNMSSET
SRCCALFEMA ECGFERKLAD DEYPHALYIQ NYSSAASSCI LLRKWIFDIS REIELCERDK
VFKELCFWQA VADVNGGLVS AKEKMFQLKA LQSIERADKY LNMVRAMDGY NRIVFPHCSC
GSRKDGDIIL GVEFSQLTIH ACDYEGNLQE EVLVFDWADI LEYKVVDNGA TFAFEYARSQ
KKPKSVKLST QFAVYMNFCF SRILEERERR AGLIFFKEEY
//
