ID A0A0K0DFA0_ANGCA Unreviewed; 339 AA.
AC A0A0K0DFA0;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Peptidase A1 domain-containing protein {ECO:0000313|WBParaSite:ACAC_0000962601-mRNA-1};
OS Angiostrongylus cantonensis (Rat lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC Angiostrongylus.
OX NCBI_TaxID=6313 {ECO:0000313|Proteomes:UP000035642, ECO:0000313|WBParaSite:ACAC_0000962601-mRNA-1};
RN [1] {ECO:0000313|Proteomes:UP000035642}
RP NUCLEOTIDE SEQUENCE.
RA Martin A.A.;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:ACAC_0000962601-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase A1 family.
CC {ECO:0000256|ARBA:ARBA00007447, ECO:0000256|RuleBase:RU000454}.
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DR AlphaFoldDB; A0A0K0DFA0; -.
DR STRING; 6313.A0A0K0DFA0; -.
DR WBParaSite; ACAC_0000962601-mRNA-1; ACAC_0000962601-mRNA-1; ACAC_0000962601.
DR Proteomes; UP000035642; Unassembled WGS sequence.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd05471; pepsin_like; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 2.
DR InterPro; IPR001461; Aspartic_peptidase_A1.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR034164; Pepsin-like_dom.
DR InterPro; IPR033121; PEPTIDASE_A1.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR PANTHER; PTHR47966:SF45; ASPARTIC PROTEASE 6; 1.
DR PANTHER; PTHR47966; BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED; 1.
DR Pfam; PF00026; Asp; 1.
DR PRINTS; PR00792; PEPSIN.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 1.
DR PROSITE; PS51767; PEPTIDASE_A1; 1.
PE 3: Inferred from homology;
KW Aspartyl protease {ECO:0000256|RuleBase:RU000454};
KW Hydrolase {ECO:0000256|RuleBase:RU000454};
KW Protease {ECO:0000256|RuleBase:RU000454};
KW Reference proteome {ECO:0000313|Proteomes:UP000035642}.
FT DOMAIN 36..336
FT /note="Peptidase A1"
FT /evidence="ECO:0000259|PROSITE:PS51767"
FT ACT_SITE 54
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
FT ACT_SITE 230
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
SQ SEQUENCE 339 AA; 36950 MW; 09B639A0E7D61FAA CRC64;
MRHTFTMNCF YRNSNESGCK KNILIRDNGD VMNHEFVGNI TLGTPDQQFA VMLDTGSADL
WVPGKNCKAE NGTSTLISFS GSGSGKQEFD SGSSSTFVGG NRTWAIKYGL GEVKGVRGTD
VMKVGNAATY VCFSDSKTIL LQDCSDGVLG LGFTSLSVDH TVPPLINAID QSLLDKPLFT
VWILGLRGLF TYGAIDTEKC GKIIAYEPLS SETYYQFKVC YQAMYEAASD TGTTFIGGPR
VIVDELAKAA GAVYNATEDL YLIECNAILP TLDITIGTKK YRIDSIYYVL KKGNTCFLAI
ISSEFGAFGP NWVLGIPFIR QYCNIFDIGQ KRIGFALSL
//
