ID   A0A0K0DNB7_ANGCA        Unreviewed;       357 AA.
AC   A0A0K0DNB7;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Pept_C1 domain-containing protein {ECO:0000313|WBParaSite:ACAC_0001324701-mRNA-1};
OS   Angiostrongylus cantonensis (Rat lungworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC   Angiostrongylus.
OX   NCBI_TaxID=6313 {ECO:0000313|Proteomes:UP000035642, ECO:0000313|WBParaSite:ACAC_0001324701-mRNA-1};
RN   [1] {ECO:0000313|Proteomes:UP000035642}
RP   NUCLEOTIDE SEQUENCE.
RA   Martin A.A.;
RL   Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:ACAC_0001324701-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase C1 family.
CC       {ECO:0000256|ARBA:ARBA00008455}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A0K0DNB7; -.
DR   STRING; 6313.A0A0K0DNB7; -.
DR   WBParaSite; ACAC_0001324701-mRNA-1; ACAC_0001324701-mRNA-1; ACAC_0001324701.
DR   Proteomes; UP000035642; Unassembled WGS sequence.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd02620; Peptidase_C1A_CathepsinB; 1.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR000169; Pept_cys_AS.
DR   InterPro; IPR025660; Pept_his_AS.
DR   InterPro; IPR013128; Peptidase_C1A.
DR   InterPro; IPR000668; Peptidase_C1A_C.
DR   PANTHER; PTHR12411:SF894; CATHEPSIN B-LIKE CYSTEINE PROTEINASE 6; 1.
DR   PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR   Pfam; PF00112; Peptidase_C1; 1.
DR   PRINTS; PR00705; PAPAIN.
DR   SMART; SM00645; Pept_C1; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR   PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035642};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Thiol protease {ECO:0000256|ARBA:ARBA00022807}.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           27..357
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018672808"
FT   DOMAIN          104..330
FT                   /note="Peptidase C1A papain C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00645"
SQ   SEQUENCE   357 AA;  39544 MW;  4FBDF6D6619AC491 CRC64;
     MGSPQRKTSF QKTAIVAVVL VTAVSAASLQ NAKKNLVETG RLTGSELVDY INKAQKLFTA
     KLSPRFANFP NEIKRRLMGS KYVALPAKYR VNEKTHSDID DTTIPKSFDS RTNWPECPSL
     YSIRDQSSCG SCWAVGAVEA MTDRICIASK GNQKVTISAD DLLSCCDECG FGCDGGYLYD
     AWSYWVTDGI VTGSNYTSKK CPKDIYPTNT CEYKCQDGYS ISYNDDKHYG ASVYSVAQDV
     ATIQKEIMTN GPVEVAFDVY EDFEHYSSGI YKHTTGDYLG GHAVKMLGWG TQNGTDYWIC
     ANSWNSDWGE NGTSRRCSES DFSEFFVVST SAKLNRASLP ENRNDALRIP YFVGGLK
//