ID   A0A0K0DPZ1_ANGCA        Unreviewed;       292 AA.
AC   A0A0K0DPZ1;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Phorbol-ester/DAG-type domain-containing protein {ECO:0000313|WBParaSite:ACAC_0001383001-mRNA-1};
OS   Angiostrongylus cantonensis (Rat lungworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC   Angiostrongylus.
OX   NCBI_TaxID=6313 {ECO:0000313|Proteomes:UP000035642, ECO:0000313|WBParaSite:ACAC_0001383001-mRNA-1};
RN   [1] {ECO:0000313|Proteomes:UP000035642}
RP   NUCLEOTIDE SEQUENCE.
RA   Martin A.A.;
RL   Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:ACAC_0001383001-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   AlphaFoldDB; A0A0K0DPZ1; -.
DR   STRING; 6313.A0A0K0DPZ1; -.
DR   WBParaSite; ACAC_0001383001-mRNA-1; ACAC_0001383001-mRNA-1; ACAC_0001383001.
DR   Proteomes; UP000035642; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.30.60.20; -; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR046349; C1-like_sf.
DR   InterPro; IPR002219; PE/DAG-bd.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR46199:SF3; FI24033P1-RELATED; 1.
DR   PANTHER; PTHR46199; RAC GTPASE-ACTIVATING PROTEIN 1; 1.
DR   Pfam; PF00130; C1_1; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00109; C1; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
DR   PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR   PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035642};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          7..58
FT                   /note="Phorbol-ester/DAG-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50081"
FT   DOMAIN          43..227
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
SQ   SEQUENCE   292 AA;  32710 MW;  68DAFAA406321AE5 CRC64;
     MSISSRRHDF QPLSTYFKIT SCDVCHGGIN FAAKPAYKCR DCLQLAHVSC SPRLILPCVP
     RTLVFTRTPS RRGQPVYHLQ EFCPSLPPMI AYPVIYCIVD LENRGLGREG IYRVPGRKDH
     DPLVPKSSRE EFIRAAQTNN IMSLNVAICD LPQPNRDTLA YLMLHLQKVA TLKELNQMTF
     QKIARCMAVP IMGQGSYRRG DIKVPSDDAG GKVRSVLQML KMSSEYWLQF LEYEECHKKS
     IGGSGTPAAS SAPCEPFSAN KSMLGTVTVP HAARSALKHT ARREQEFFDS TQ
//