ID A0A0K0DRF6_ANGCA Unreviewed; 331 AA.
AC A0A0K0DRF6;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Neurotransmitter-gated ion-channel ligand binding domain protein {ECO:0000313|WBParaSite:ACAC_0001434501-mRNA-1};
OS Angiostrongylus cantonensis (Rat lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC Angiostrongylus.
OX NCBI_TaxID=6313 {ECO:0000313|Proteomes:UP000035642, ECO:0000313|WBParaSite:ACAC_0001434501-mRNA-1};
RN [1] {ECO:0000313|Proteomes:UP000035642}
RP NUCLEOTIDE SEQUENCE.
RA Martin A.A.;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:ACAC_0001434501-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A0K0DRF6; -.
DR STRING; 6313.A0A0K0DRF6; -.
DR WBParaSite; ACAC_0001434501-mRNA-1; ACAC_0001434501-mRNA-1; ACAC_0001434501.
DR Proteomes; UP000035642; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005230; F:extracellular ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR CDD; cd18990; LGIC_ECD_GABAAR; 1.
DR Gene3D; 2.70.170.10; Neurotransmitter-gated ion-channel ligand-binding domain; 1.
DR InterPro; IPR006202; Neur_chan_lig-bd.
DR InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR InterPro; IPR006201; Neur_channel.
DR InterPro; IPR018000; Neurotransmitter_ion_chnl_CS.
DR PANTHER; PTHR18945:SF569; ACETYLCHOLINE-GATED CHLORIDE CHANNEL SUBUNIT ACC-2; 1.
DR PANTHER; PTHR18945; NEUROTRANSMITTER GATED ION CHANNEL; 1.
DR Pfam; PF02931; Neur_chan_LBD; 2.
DR SUPFAM; SSF63712; Nicotinic receptor ligand binding domain-like; 2.
DR PROSITE; PS00236; NEUROTR_ION_CHANNEL; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000035642}.
FT DOMAIN 6..63
FT /note="Neurotransmitter-gated ion-channel ligand-binding"
FT /evidence="ECO:0000259|Pfam:PF02931"
FT DOMAIN 97..172
FT /note="Neurotransmitter-gated ion-channel ligand-binding"
FT /evidence="ECO:0000259|Pfam:PF02931"
SQ SEQUENCE 331 AA; 38230 MW; 18BF41AD88EC12B7 CRC64;
LLNGTGYNKF RIPEDDGMTI YVEIWIQAIT SINELTNDFE MDIYITEKWL DPALNFENLS
PCKGNTIEIS SMVKRFTRQT ITCSYSARTA NLRAECNLSL NHQVLDRLWT PNSCFVNSKV
AQIHDSPFRS VFLMLFPNGT VMVNYRVRVK GPCSLELSNF PLDLQTCGLI YERLNILRLE
FRIPEKVDNV CCKLNTPKEH TNENNFNYNN QEVRMRWSNT DEPVRPMAPI VLPDFDLFKI
TANRKEELIP ALSAISGGHV GRTACDDYVR TTVHLVFYAG IFTDVSYDFY QVAQLIRVMW
APNFPYHIHD HSFASFVTHM IRCAIQQPPY S
//
