ID A0A0K0DZF9_STRER Unreviewed; 224 AA.
AC A0A0K0DZF9;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=RIIa domain-containing protein {ECO:0000313|WBParaSite:SSTP_0000262100.1};
OS Strongyloides stercoralis (Threadworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=6248 {ECO:0000313|WBParaSite:SSTP_0000262100.1};
RN [1] {ECO:0000313|WBParaSite:SSTP_0000262100.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (AUG-2015) to UniProtKB.
CC -!- FUNCTION: May be involved in cooperative interactions with calmodulins
CC or calmodulin-like proteins (By similarity). Recruits calmodulin
CC proteins to microtubules, thus being a potential scaffold in cellular
CC signaling and trafficking (By similarity). May associate with nucleic
CC acids and regulate gene expression at the transcriptional or post-
CC transcriptional level. {ECO:0000256|ARBA:ARBA00024682}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the IQD family. {ECO:0000256|ARBA:ARBA00024341}.
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DR AlphaFoldDB; A0A0K0DZF9; -.
DR STRING; 6248.A0A0K0DZF9; -.
DR WBParaSite; SSTP_0000262100.1; SSTP_0000262100.1; SSTP_0000262100.
DR Proteomes; UP000035681; Unassembled WGS sequence.
DR Gene3D; 1.20.5.190; -; 2.
DR Gene3D; 1.20.890.10; cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain; 1.
DR InterPro; IPR003117; cAMP_dep_PK_reg_su_I/II_a/b.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR32295; IQ-DOMAIN 5-RELATED; 1.
DR PANTHER; PTHR32295:SF10; PROTEIN IQ-DOMAIN 26; 1.
DR Pfam; PF00612; IQ; 3.
DR Pfam; PF02197; RIIa; 1.
DR SMART; SM00015; IQ; 3.
DR SUPFAM; SSF47391; Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 3.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000035681}.
FT DOMAIN 15..47
FT /note="RIIa"
FT /evidence="ECO:0000259|Pfam:PF02197"
FT REGION 201..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 224 AA; 25768 MW; 0F6BBDD10604C8C2 CRC64;
MAEQLSDKYK IPETLRPLLE ALARETIRAQ PTDVVSFGKL FFDILSHHQQ DSDKSILTDN
VSYDMFRMDL QQRYKNIMLK ENMTRSVSPE DVAATKIQAA FRGHQVRMHP ERYGVDAELV
RRRSSDKLAT LDFNKDQKRH SIGGYSLEHS QTPENRAATK IQAEFRGYLA RKNIQAMREQ
NDNAATKIQA HVRGFLTRKR LGKEGLISPS RSHSSLQSHK SEEN
//
