ID   A0A0K0E094_STRER        Unreviewed;       372 AA.
AC   A0A0K0E094;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Major sperm protein {ECO:0000256|RuleBase:RU003425};
OS   Strongyloides stercoralis (Threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=6248 {ECO:0000313|WBParaSite:SSTP_0000290800.1};
RN   [1] {ECO:0000313|WBParaSite:SSTP_0000290800.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (AUG-2015) to UniProtKB.
CC   -!- FUNCTION: Central component in molecular interactions underlying sperm
CC       crawling. Forms an extensive filament system that extends from sperm
CC       villipoda, along the leading edge of the pseudopod.
CC       {ECO:0000256|RuleBase:RU003425}.
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DR   AlphaFoldDB; A0A0K0E094; -.
DR   STRING; 6248.A0A0K0E094; -.
DR   WBParaSite; SSTP_0000290800.1; SSTP_0000290800.1; SSTP_0000290800.
DR   Proteomes; UP000035681; Unassembled WGS sequence.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR000535; MSP_dom.
DR   InterPro; IPR008962; PapD-like_sf.
DR   Pfam; PF00635; Motile_Sperm; 1.
DR   SUPFAM; SSF49354; PapD-like; 1.
DR   PROSITE; PS50202; MSP; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|RuleBase:RU003425};
KW   Cytoskeleton {ECO:0000256|RuleBase:RU003425};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035681}.
FT   DOMAIN          5..121
FT                   /note="MSP"
FT                   /evidence="ECO:0000259|PROSITE:PS50202"
FT   REGION          132..372
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        132..238
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        246..271
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        272..295
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        296..372
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   372 AA;  43699 MW;  A8D6918FF64F0A80 CRC64;
     MTTFPLEVEP SHVLAFDVSS TSRAKAQIIL KNNSNKKYVV KFKSHKNSAF KFLPVVTVVE
     RRSEITVEVL FKGDEKYMST NCNDNIAICV LETTKELPPR EIFMSADEDD IEYMFLTSIF
     LKTKDDAEKF KNFDNKKEKN GKKGENNKKE KKSNKEKNTK EEKKDNEEKK DNEEKKDSEE
     KNDNEEKNNN EEKDNNNDKK NNNEKKNNKS KKEKNDNAEK ENEENKNDKP KKEVKQSDDG
     ENEDDEDNKQ GKKKKKNKDI ENEDNQENKQ SRRKKKNGKY GSKRDSKHKK RTKKIKNGNN
     ENEDKYDNKL KQRKKKPQND ENEDNGNKIN KPKKGKKGVK VVEKEDEDND KDENVKKEKK
     TEVTEKETDE KD
//