ID A0A0K0E3Y0_STRER Unreviewed; 522 AA.
AC A0A0K0E3Y0;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=MFS domain-containing protein {ECO:0000313|WBParaSite:SSTP_0000420000.1};
OS Strongyloides stercoralis (Threadworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=6248 {ECO:0000313|WBParaSite:SSTP_0000420000.1};
RN [1] {ECO:0000313|WBParaSite:SSTP_0000420000.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (AUG-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A0K0E3Y0; -.
DR STRING; 6248.A0A0K0E3Y0; -.
DR WBParaSite; SSTP_0000420000.1; SSTP_0000420000.1; SSTP_0000420000.
DR Proteomes; UP000035681; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR11662:SF60; MFS DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11662; SOLUTE CARRIER FAMILY 17; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Ion transport {ECO:0000256|ARBA:ARBA00023201};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000035681};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00023201}.
FT TRANSMEM 20..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..486
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..489
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 522 AA; 58901 MW; 704F6DC1AE20249A CRC64;
MERKKSSSFW SFKSRRMHVI ILLMFGWGIM AFTRHQLGIS LPCMLNSTAI EEASSNKSNK
NDINLDELEN AKECLKINNV KNISYFIDKK IVIDYGGTFN WTYNQQDLVI SGTYFGSIIT
VLPAGYFSDK ISPRNIMIYG SIIYIITSIS FPKLVIAFGY LPGFITRFIM GLGEGMLLPA
SSSMLSRWFP NSEKPLASTL LTVGNQMATF IGNPLAAFFC KSSIGWSGTF YTCGIVLFIW
IILWYYFVQN SPSTAKWISI NEKEYLEKET GFRLIKKEKN KKFKIPWKSF LTSSAFYCTF
PCFFFGNMHG VFLSMYLPLY YKEKLYVDVV NNGFMSAVPT IIQMIVKIIW SSCTERLQKK
NYITSNTSVK VSQIVSSILL PVGLIMVDST LDCTNPWITV IYICIANCGY GIATSGYLTS
IISMAPAITG LLSGITNIAA ITSRILTPFI FSFIRKTKII DVWSGIFYGI AINWFISSLI
FIYWGVGEAQ EWGIIKDTTE TESITETNES LKSKTTSISS NK
//
