ID   A0A0K0E4W2_STRER        Unreviewed;       677 AA.
AC   A0A0K0E4W2;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=DEAD/DEAH box helicase {ECO:0000313|WBParaSite:SSTP_0000453100.1};
OS   Strongyloides stercoralis (Threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=6248 {ECO:0000313|WBParaSite:SSTP_0000453100.1};
RN   [1] {ECO:0000313|WBParaSite:SSTP_0000453100.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (AUG-2015) to UniProtKB.
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DR   AlphaFoldDB; A0A0K0E4W2; -.
DR   STRING; 6248.A0A0K0E4W2; -.
DR   WBParaSite; SSTP_0000453100.1; SSTP_0000453100.1; SSTP_0000453100.
DR   Proteomes; UP000035681; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 1.10.3380.30; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR012961; Ski2/MTR4_C.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF7; EXOSOME RNA HELICASE MTR4; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08148; DSHCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035681}.
FT   DOMAIN          50..207
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          265..461
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   677 AA;  77482 MW;  BBCF5F8C2AA4B400 CRC64;
     MSFSKIIAED DVFRHEVVNN ENIEYGMFFN QMPDLKIVDF DIDNFQKHSN RCLDRMENLV
     LAAHTGSGKT IAARYAIELG LKEGKRVVYT GPIKSLINQK YYEFKNAYPN KVGIITGDRV
     VDSDKDIIVM VTEVFEKMCH EHRRYMEKIA HVIYDEAHFM GDLQRGKIWE MSIINCPRNI
     NLLLLSATIE NSKQVAAWIS KIKMKPCHLI TTKRRFIPLE YHVYLSNDNT IYTVKDKDGK
     IYKKALEKVK NGVIAEGVSK KSLCNVLEKL TAANYIPALF YCSSRKFCDK FAMFAEHKFD
     LLNKDEKENM LTAINGTLEK YMNNQVLMRE MMTYKDQFLR GIAVHHSGLL KITRDFIEKC
     LEYKHIKVIF TTETLAVGLN CPVSACVFTD FKKFDGVVQR VFNYGEFTQM AGRAGRRGID
     EKGVVVLMSN KNLDVDALEK ILESKSTPMN SQLAIDYGFI LDMCSQNDYG KVLKNSFRNF
     QHNTLEADIS LFEKRREILK ELEFIGSDNQ LTKKGAFAAC ISYNPGALVI ASLIENSNLF
     NSDIQKSAAI LSLFVCPQDL SNKTCMEAAG PISMITEIKE NINRIEENNG ISENERLNIE
     CCSLFFKNII ELIGGRSLQK VVDDSEFYAG IILKIIKDVK QIAEKIASVT KEEKKLHFME
     LMDALTEFLK DDKIFEY
//