ID   A0A0K0E589_STRER        Unreviewed;       536 AA.
AC   A0A0K0E589;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Endochitinase {ECO:0000313|WBParaSite:SSTP_0000467300.1};
OS   Strongyloides stercoralis (Threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=6248 {ECO:0000313|WBParaSite:SSTP_0000467300.1};
RN   [1] {ECO:0000313|WBParaSite:SSTP_0000467300.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (AUG-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. Chitinase
CC       class II subfamily. {ECO:0000256|ARBA:ARBA00009121}.
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DR   AlphaFoldDB; A0A0K0E589; -.
DR   STRING; 6248.A0A0K0E589; -.
DR   WBParaSite; SSTP_0000467300.1; SSTP_0000467300.1; SSTP_0000467300.
DR   Proteomes; UP000035681; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0008061; F:chitin binding; IEA:UniProtKB-KW.
DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.10.50.10; -; 1.
DR   Gene3D; 2.170.140.10; Chitin binding domain; 2.
DR   Gene3D; 3.20.20.80; Glycosidases; 2.
DR   InterPro; IPR002557; Chitin-bd_dom.
DR   InterPro; IPR036508; Chitin-bd_dom_sf.
DR   InterPro; IPR011583; Chitinase_II.
DR   InterPro; IPR029070; Chitinase_insertion_sf.
DR   InterPro; IPR001223; Glyco_hydro18_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR11177; CHITINASE; 1.
DR   PANTHER; PTHR11177:SF317; CHITINASE 11; 1.
DR   Pfam; PF01607; CBM_14; 2.
DR   Pfam; PF00704; Glyco_hydro_18; 2.
DR   SMART; SM00494; ChtBD2; 2.
DR   SMART; SM00636; Glyco_18; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR   SUPFAM; SSF57625; Invertebrate chitin-binding proteins; 2.
DR   PROSITE; PS50940; CHIT_BIND_II; 2.
DR   PROSITE; PS51910; GH18_2; 1.
PE   3: Inferred from homology;
KW   Chitin-binding {ECO:0000256|ARBA:ARBA00022669};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035681};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..536
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5005327699"
FT   DOMAIN          32..370
FT                   /note="GH18"
FT                   /evidence="ECO:0000259|PROSITE:PS51910"
FT   DOMAIN          398..455
FT                   /note="Chitin-binding type-2"
FT                   /evidence="ECO:0000259|PROSITE:PS50940"
FT   DOMAIN          484..536
FT                   /note="Chitin-binding type-2"
FT                   /evidence="ECO:0000259|PROSITE:PS50940"
SQ   SEQUENCE   536 AA;  59635 MW;  679E8B00883C331D CRC64;
     MYSLIHWLFI FLSLQGIFFT ATLSALSQDT QYIRPCYFTN WAQYRQGQGK FLPEDYIPGL
     CTHILFAFGW MNEDYTAKAY DPADLPNDWA GAGMYSRINS LKQKDPNLKT LLSFGGWTFG
     TRLFEVLLGF FNKVNYVAFI KELRLAADEE STKTGKDRLL ITAAVSAAVE TIRSGYDIPA
     LADYFDFILL MSYDFHGTWE SQTGFNAPLY PRIGETNTDW NVAGAAHYWA QHGMPKNKII
     IGAATYGRGW TLTNSKEFGV GAAGTKATTT KFVGEAGVGA YYEFCEMLAQ GATRYWDDQA
     KVPYLVFGDQ WFSYDDVESI QYKAEFVKEH GFGGMFIWTL DFDDFGGRCS GGGNIKYPLI
     SKISEVLGGK TLSITSSTPK STTTLKIVPS TSSENELEGF CDELSDGFHS LAPYSCIQFM
     LCLNKSSYLM ECPSNLQYNE KIGYCVLPKD SGCSSSFPPT TIITSTVSTT TITSTVSTIK
     KVEKFVCIVD GFHADPNSCF RFYRCVNLTP YLFDCPGGLA YNKEAKLCDR IGVSGC
//