ID   A0A0K0EDU0_STRER        Unreviewed;       870 AA.
AC   A0A0K0EDU0;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Importin N-terminal domain-containing protein {ECO:0000313|WBParaSite:SSTP_0000765200.1};
OS   Strongyloides stercoralis (Threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=6248 {ECO:0000313|WBParaSite:SSTP_0000765200.1};
RN   [1] {ECO:0000313|WBParaSite:SSTP_0000765200.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (AUG-2015) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the importin beta family. Importin beta-1
CC       subfamily. {ECO:0000256|ARBA:ARBA00010907}.
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DR   AlphaFoldDB; A0A0K0EDU0; -.
DR   STRING; 6248.A0A0K0EDU0; -.
DR   WBParaSite; SSTP_0000765200.1; SSTP_0000765200.1; SSTP_0000765200.
DR   Proteomes; UP000035681; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR040122; Importin_beta.
DR   PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR   PANTHER; PTHR10527:SF1; IMPORTIN SUBUNIT BETA-1; 1.
DR   Pfam; PF13513; HEAT_EZ; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000035681}.
FT   DOMAIN          22..102
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
SQ   SEQUENCE   870 AA;  96790 MW;  FA5B60840291A3A6 CRC64;
     MNQLLETLEK TISNNPADQK LALDFLNQAS EQNFAVYILE LSKVLKHTGH PNHVRQAAGI
     QLKNCLVAKE EETKLHYADR WLSLPENIRL EVRTNVVETI GTEQFRPSAA SQCVAAIAGI
     EIPRNMWPDA IKILSECVSN SNANVLAKEV SLEALGYICQ DLDATVLEAN SNTILTAIVY
     GMRREETNVN IKRAAVKALL NSLEFTRNNF SIEEQRNHIM TIICDATQDD DKQVKVCSLE
     CLVKVMSLYY SVMQPYMAPA LFPISISAMK SDVDDIKLQG IEFWSNVAEN EIAFICEAEE
     AKESGIQPTQ FSQYYAKGAL QYICPIILNV LVKVDEDDDD DEWTPSKSAG VCLQLLAQCT
     GDDICQYVLP FITENFKHQD WRYREAAVMA FGCIMEGPDK AKLNELISHA LGSLIETLGD
     SHIAVRDSAA WTLGKACELS MEIVTKPDVL QLLLPALSNS LLQEPRVAAN ICWTISSLAR
     AAYEVASLES GVEEPETFVL SSCFEAMVGE LLKTTDRPDG NISNLRIAAY ETLMEMIKNS
     PKDCYPSVQK TTLNVLQKME QLLQLEDSIE SSTDKSQLRN LQSLLCATLQ SVIKKIRRED
     TPLISDTIMN CILQIMQRCQ GKDVGGVMED ALLTVSALVE SLGRGFGKYV TAFRPYLLLS
     LKNYKEGVVF LSALGVLTDL CREFEKDICF MLDECIQILI EVLHAPDSDK YLKADILACF
     GDIALAISDD FKRYFSMSMD LLCSASKAAK ITNYSDYEQI EYVEHLRSSC VTAFSSICQA
     YPMVNELKAY VVSIVELIVS IGSEEDIPDT LLGHSCGLLG DIIKLFGADL LPLLNNTILD
     DLLNRGRRST KAKSTAIYAT KELRKIKPMS
//