ID   A0A0K0EEF4_STRER        Unreviewed;       382 AA.
AC   A0A0K0EEF4;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Sodium channel protein Nach {ECO:0000313|WBParaSite:SSTP_0000786600.1};
OS   Strongyloides stercoralis (Threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=6248 {ECO:0000313|WBParaSite:SSTP_0000786600.1};
RN   [1] {ECO:0000313|WBParaSite:SSTP_0000786600.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (AUG-2015) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|ARBA:ARBA00007193,
CC       ECO:0000256|RuleBase:RU000679}.
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DR   AlphaFoldDB; A0A0K0EEF4; -.
DR   STRING; 6248.A0A0K0EEF4; -.
DR   WBParaSite; SSTP_0000786600.1; SSTP_0000786600.1; SSTP_0000786600.
DR   Proteomes; UP000035681; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.287.820; Acid-sensing ion channel domain; 1.
DR   Gene3D; 1.10.287.770; YojJ-like; 1.
DR   InterPro; IPR001873; ENaC.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   PANTHER; PTHR11690:SF273; DEGENERIN LINKED TO MECHANOSENSATION; 1.
DR   Pfam; PF00858; ASC; 1.
DR   PRINTS; PR01078; AMINACHANNEL.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035681};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT   TRANSMEM        335..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   382 AA;  44009 MW;  E3A4F83267412292 CRC64;
     MSLIEIPELM NLADYNDLMK GQEELEKYIN NTHENFSIND FIFNAGFECK DMLRICSLGG
     KEFNCCSAAR PVLTKNGKCF EINLKSSNLK WLHNPIRLGV DNGLMIIADY HSEEQLFFDT
     DIAEESLFGD IFQKGFRYSM HEKKAGNPFA SEDSTASPGT RVFTALNVEY NKLLENNNWG
     NCTKTWPSKY KDKREYSSKI CKTLCRAKYF NDLCGCTPYP YNIDGKYNVC TPYKLYNCIK
     KDKNYLNGNF LLSKCQECSP DCESWIYSAY NSYGGEFPSE ALYKLAGRNK TWTPNFIKNN
     FVAVNIFFKD NSYTYYEQIK ATTVSEVLSN IGGSMGLFLG MNIISVGEIY IYLLRIFWIC
     VSKKRRRNVM EKKKRSSSQI TV
//