ID A0A0K0EFI3_STRER Unreviewed; 718 AA.
AC A0A0K0EFI3;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Eukaryotic translation initiation factor 3 subunit B {ECO:0000256|PIRNR:PIRNR036424};
DE Short=eIF3b {ECO:0000256|PIRNR:PIRNR036424};
OS Strongyloides stercoralis (Threadworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=6248 {ECO:0000313|WBParaSite:SSTP_0000824600.1};
RN [1] {ECO:0000313|WBParaSite:SSTP_0000824600.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (AUG-2015) to UniProtKB.
CC -!- FUNCTION: Component of the eukaryotic translation initiation factor 3
CC (eIF-3) complex, which is involved in protein synthesis and, together
CC with other initiation factors, stimulates binding of mRNA and
CC methionyl-tRNAi to the 40S ribosome. {ECO:0000256|PIRNR:PIRNR036424}.
CC -!- SUBUNIT: Component of the eukaryotic translation initiation factor 3
CC (eIF-3) complex. {ECO:0000256|PIRNR:PIRNR036424}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR036424}.
CC -!- SIMILARITY: Belongs to the eIF-3 subunit B family.
CC {ECO:0000256|PIRNR:PIRNR036424}.
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DR AlphaFoldDB; A0A0K0EFI3; -.
DR STRING; 6248.A0A0K0EFI3; -.
DR WBParaSite; SSTP_0000824600.1; SSTP_0000824600.1; SSTP_0000824600.
DR Proteomes; UP000035681; Unassembled WGS sequence.
DR GO; GO:0005852; C:eukaryotic translation initiation factor 3 complex; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0031369; F:translation initiation factor binding; IEA:InterPro.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR011400; EIF3B.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR013979; TIF_beta_prop-like.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR14068; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED; 1.
DR PANTHER; PTHR14068:SF0; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B; 1.
DR Pfam; PF08662; eIF2A; 1.
DR PIRSF; PIRSF036424; eIF3b; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR036424};
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000256|PIRNR:PIRNR036424};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW ECO:0000256|PIRNR:PIRNR036424};
KW Reference proteome {ECO:0000313|Proteomes:UP000035681};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PIRNR:PIRNR036424};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT DOMAIN 404..606
FT /note="Translation initiation factor beta propellor-like"
FT /evidence="ECO:0000259|Pfam:PF08662"
SQ SEQUENCE 718 AA; 82467 MW; 20A8188E0E046266 CRC64;
MALVLNLNVN TDEKNLKESL EDKYADPEGF VDEEPAIRAR EELMEKMPRK NKYEERCVIV
FGIPIIGKER VQKLSNVLKK IIGSTSEEFE ETIPLSPEGG TKGLLFIEYP NKEIASKGAD
LLNGYVLDKN HTFKAMTITN VKNIQKPDPN WKKPEVREYV DAGNVYSHLT HKKCLDQFGV
QYCSGRERDA AQLGVYWFQR EQEPVLADSE ANRANWSELP FRWSPKGSYI TTLHSLGVQI
WGGPTFNRIQ RFSHPQPVLV DFSPQERFIV VFSNPFSSFQ GNKSTAVCCT IFNIMSGDVV
KQFTALQLGL TKEDSKPSWP IFKWSHDDKY CGYIKRKSDS AIIFNTDDFS SSDSLPLSNV
SKIEWSPCNN RIAYYCQENI KTSAPAEIGI MSYPMKDKLR AARVFNCSKA ELFWHTSGRF
FAVVSERYGK RTVKENEVKY FNITTHIDIF DCSVKDIPLL NHTIDDQFKS FAWDPSSEKF
AILCGTSTKT TSYIFNVEKT KHVPTLLLKL DEPSIHNTLK FSPFGGWLVI AGCKNIGGGS
LVFVDCSTNE PTKMKTTDHS DMTSCKWDPT GRYFVSLCSK PRADNGYIIY NFQGKTLYKA
QYDVLIRFDW RPRLKLDGHE SRVAEVKKNF KKFTSQFEEE DRIEKDAVYR DIVVKRREIY
EDFMKIREAY LKQYAIEAPI RKELRNGVDT DKLFENCEYV NHEVTVVVRS SETSEPSN
//
