ID A0A0K0F7I2_STRVS Unreviewed; 941 AA.
AC A0A0K0F7I2;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Sorting nexin-13 (inferred by orthology to a human protein) {ECO:0000313|WBParaSite:SVE_0477900.1};
OS Strongyloides venezuelensis (Threadworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=75913 {ECO:0000313|Proteomes:UP000035680, ECO:0000313|WBParaSite:SVE_0477900.1};
RN [1] {ECO:0000313|Proteomes:UP000035680}
RP NUCLEOTIDE SEQUENCE.
RA Martin A.A, De Silva N.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:SVE_0477900.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (AUG-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR AlphaFoldDB; A0A0K0F7I2; -.
DR STRING; 75913.A0A0K0F7I2; -.
DR WBParaSite; SVE_0477900.1; SVE_0477900.1; SVE_0477900.
DR Proteomes; UP000035680; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF3; SORTING NEXIN-13; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000035680};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 102..286
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 383..498
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 565..687
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
SQ SEQUENCE 941 AA; 108121 MW; 19C8F066BA7843E3 CRC64;
MDLSVSNRKT IFTYSILVGI TSILHYFELL YINLYVIICF LFGFCYVIFH QSNVVIQPKK
RSLDEVAENF KFSPGINSLL KELKDSFERN TGHKERHSMA SSPEVDAILE QILTYFMRDF
VDNWYSGICS DSGFQESLKR MIRRTISAFS FCLSKVDWQE LLTRDIVDDV ASHFRLFRKA
KEKLDLKKEM RYNNLESLFF DVELEMEKNY CRDLVSTTPE YEIAYFKDVV DILLYLLMPS
EDFRCRPLRF ILRDILVNRI FVPCFDKLSN PDYVNYMIVW LLSEVNIDTD AFILSLETSH
SVPELEATLE SIDEEINGLK SKDRGREFLD IVHQQIASLE FAAEIIKKRM VVLTSHPDLE
ILSEIEIGEQ INSDLVQLPI TVIMTNNVAI SYFTKFLRKH GGQNYIDCFL AIEGFKVSTE
QQFKALAGGE VQEKDVAKVV KDSALFLYHQ FLSQEAKTRV PLDENIINKF LARLRNDEPA
DTWFEAIEDK LIDILSKENQ YYPAFKKSNE YIDLLIELGI LLASDLNKDD ESIVDEEDGK
SISSLGSFTS LEFSQPSVEC LKRNLATSVV IEHLGIGHQG QKSFILYNVR ARKESSDETS
TSEWNVIRRY SDFYKLNQIV KEKYPKLKHI SFPGKKAFNN FDTMFLEKRS TALNLYVNTL
LETNILEANN GLDSIIYDFL TQKTYTGIKE GLSKKVISSL FNPVVTSVKA IGTVVTSVPD
QVLDGVTKVS TGINRAASQV LNTMGSKSDD LSDYSRVAAD IQNETFSDNI PLRVLLLFVD
EVFVLRGRGQ WFRRQLTSLL HQIISATLGG SINKKIIDLV NWLTSSEQVV QYLIAFRETM
WPNGILNTKQ EIRSLSSSLR TRLFAKTQMY ALIPDELKIF IGTNVAVRGV SNISDCLQNR
HLNRRLIYVI LERFLVKIFP NNRFEKILPQ LHSKSPRKTT A
//
