ID   A0A0K0F917_STRVS        Unreviewed;      1533 AA.
AC   A0A0K0F917;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=LSDAT_euk domain-containing protein {ECO:0000313|WBParaSite:SVE_0531800.1};
OS   Strongyloides venezuelensis (Threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=75913 {ECO:0000313|Proteomes:UP000035680, ECO:0000313|WBParaSite:SVE_0531800.1};
RN   [1] {ECO:0000313|Proteomes:UP000035680}
RP   NUCLEOTIDE SEQUENCE.
RA   Martin A.A, De Silva N.;
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:SVE_0531800.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (AUG-2015) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   STRING; 75913.A0A0K0F917; -.
DR   WBParaSite; SVE_0531800.1; SVE_0531800.1; SVE_0531800.
DR   Proteomes; UP000035680; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR041491; TRPM_SLOG.
DR   PANTHER; PTHR13800:SF45; GON-TWO LIKE (TRP SUBFAMILY); 1.
DR   PANTHER; PTHR13800; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF18139; LSDAT_euk; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035680};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        977..999
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1005..1022
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1043..1063
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1114..1134
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1181..1206
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          158..426
FT                   /note="TRPM SLOG"
FT                   /evidence="ECO:0000259|Pfam:PF18139"
FT   DOMAIN          979..1212
FT                   /note="Ion transport"
FT                   /evidence="ECO:0000259|Pfam:PF00520"
FT   REGION          1376..1414
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1330..1371
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1533 AA;  176825 MW;  A126DC242FFC3D67 CRC64;
     MSESSIHHVS MLNINKKESD KIGFSSIFGV CSDGSEETIS SYHRNNMHKK KYPFKEKDSM
     TKEFNDKIQN CWIEKTFKIR ECIKFIPSSN EKDKCCCGNY SSYHSHKALS RFTTAIINKK
     YCKTINNKKW NILEHTETKN TDSYGTIEFQ GENHAHKAYY CRVGFDSNPK DILYLMENIW
     KLEAPNLIIT IHGGMANFEV QQKLGKVFRE GLLKAAQTTG AWIITSGIDS GVVRHVAKAL
     DDAGISARMR SKIILLGIAP YGLLSNREKF VGKNIVVPLD HQPYSVRNNY TMLNDRHSYF
     LLVDNGTVGR YGADMILRKR FENYLSQGDN INYPVKHVPI ICVVLEGGIC TLESALQYVT
     SKPPCPVVVC DGSGRISDLL AFAQKNLLPN GLLSIPVRND LENLIKKVFN ADQNTAHEIL
     NNIMKCVNQR DLLTIYRYGE EGAKDVDYAI LTAILRGQNL SPMDQLYLTL TWNRVDIARS
     HIFAKNKEFN STVLYSTLMD ALLLERIDFV KLLFENGVNL CKFLTVTRLE ILYNFDKHEI
     LSLLQFLIGT QAESKRYKNL TLFDIGIIIE KLMGNAYRSN YTTRRFKSKN GISSKSKSNF
     FPPNNSKVGS LILSSGNCST NSIFCNGRNE TLKETEFGGG NSYIPHDSME LKEEVEFSFP
     LNELMIWVIL TKRHELAKFL WQYGEEAMAR SLIAIRLYKG MAKVASDDYT ALEVSAILRE
     HASDFKKLSL ELLEHCYQQD DKQTRKMLTT QLPNWGHHTC LSLAFLANNK EFLAHPCCQV
     LLAELWYGGL RFRSQSNIKV IAAVLFPPTI LLLDFKSSAC NLPNNISIEK KDIHLVENDN
     NYSIRNYGNN SENKITTGME ENEIEGENYF RFPSREHLSQ KRRSVVSLTY NSFFSEGQWG
     WKKLLGKNEN LKDNEGTCTL NSPYIEKQKN YIYENSCNLE NKSEKYQKLS LGKKFQHWII
     LLFYKLLLFY RAPITSFWIW AISFGVFLTT FTFILLVELP VEPSIYEWYI FVYVVSITLE
     HLRKLLTLES SSVMEKIRVF YNTTYWHILT ATAIITYFFG FAFRLNKEMI HTHGRIILSI
     NSVFWHMKLF DFLSVHPKIG PYITMAGKMV LNMSYIIVML LVTLMAFGLS RQAITYPHEK
     FNWLLVRNIF YKPYFMLYGE VYAGEIDTCG DEGTNCVPGG WIPPIIMTIF LLVANILLIN
     MLIAIFNNIF TITNAMSQQV WMFQRYSQVL EYEDTPIIPP PFTPLIHLYL IIRTLIKWSV
     RKKNSITQTT GINKVKNMMP FAIKVHMTKD ELRQIHDFEE DCMDDLCRKK NNLVKKKCET
     DNNDAYHENL EIMTGKIIEL INENQNLKSN INKIQEDLKN IEENQRFMLQ MVIQNREKRR
     SSGAANDTDI KYTSTSENIE DPDSENDEPF TRSRIPTYVG DKIPLRHHVL PQYTSITDGL
     SNKLRLREWH KLSLSRYSQV DSQLGNEANF DINVNEIKSS NFLSDMQDMM KINNDEDNLY
     FNPLCPKVSC HHSIFTVDNS PTTVFLQSST KNN
//