ID A0A0K0FKN8_STRVS Unreviewed; 1278 AA.
AC A0A0K0FKN8;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=FMRFamide receptor (inferred by orthology to a D. melanogaster protein) {ECO:0000313|WBParaSite:SVE_0960200.1};
OS Strongyloides venezuelensis (Threadworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=75913 {ECO:0000313|Proteomes:UP000035680, ECO:0000313|WBParaSite:SVE_0960200.1};
RN [1] {ECO:0000313|Proteomes:UP000035680}
RP NUCLEOTIDE SEQUENCE.
RA Martin A.A, De Silva N.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:SVE_0960200.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (AUG-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
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DR AlphaFoldDB; A0A0K0FKN8; -.
DR STRING; 75913.A0A0K0FKN8; -.
DR WBParaSite; SVE_0960200.1; SVE_0960200.1; SVE_0960200.
DR Proteomes; UP000035680; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008023; C:transcription elongation factor complex; IEA:InterPro.
DR GO; GO:0008528; F:G protein-coupled peptide receptor activity; IEA:InterPro.
DR CDD; cd14978; 7tmA_FMRFamide_R-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR019427; 7TM_GPCR_serpentine_rcpt_Srw.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR019535; ICE2_C.
DR PANTHER; PTHR47323; FMRFAMIDE PEPTIDE RECEPTOR FAMILY-RELATED; 1.
DR PANTHER; PTHR47323:SF4; FMRFAMIDE PEPTIDE RECEPTOR FRPR-18; 1.
DR Pfam; PF10324; 7TM_GPCR_Srw; 1.
DR Pfam; PF10505; NARG2_C; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|RuleBase:RU000688};
KW Reference proteome {ECO:0000313|Proteomes:UP000035680};
KW Transducer {ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..283
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 644..669
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 998..1025
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1255..1278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1278 AA; 147139 MW; 11FBF14303C7AB26 CRC64;
MDNQYTYMVV LLIIICTGIV GNICSFLVYT RYATSINILL TALSVIDICL LTLATPVFVL
PFMHRIFMED SFQAYVLQYI YPLNCISQTC SVYVMVFITI ERWTAISKPL QVRSWCTTKS
AKIILIGVII FATIYNIPRF LEYEIIKDNE GHTTYKRTLR DTVLHPNYMV YYYTLLYLLT
HFCIPFAAII FFNSHVIFII LKQKKARLNF TSQQRKEIKT TVMLIIVTIM FAICNVLTFI
MNLWENINPT LFSDPKTLTM AYMFNDLANF LVILNSASTF IIYFLFSEKY RILLFDIFHY
GCSKTKGENY YNSTFSRSHS MRHQSSIYGR ISSKKSSTSL TSANDNFKRL NSINNNRLSV
NSQDIPFKCD LSRDQKSITP IYEANKEYPN TRTLSVQNKN QQLNILPKLY FTPKTCNITL
KIAKISIRIV TCVIISFIFF IYRAILKYLI CIYIPMDSDS ELQICEQPET SDLMDEKYSP
ANFQKGNEEQ IENSCDNVKI NINKGDEIPK VCPSFSKVDK TEDQPDCNSD LVVKNNITSK
FQNDSKNIMK KKSQSTNRKF LTPLMKNALK QSRQEVSLLD RTKKTEKKDQ NITIAKSIDL
VEKVEAKPNR VRSAICIDAS EAPPMKMAKK PKPSNSLLNK ITNIKQNSSS KSLPKTSLPA
TSGSSVESTK LNRLPSNLVI SNLKKQYNCS KEEAVRKFVE KCRENNSKVD NASNAEDNKL
RVQADEMPWI PNFIFPDRNQ FTSLSDADHK RYVAIIMNLI NQNPEFRFVH NVTELKDFDN
RLLSERKLFH KISFEAIDSK KKSCYRFKLP SWNKMMYSFT EARSKDLKKF SKDDYEVIDN
YEFNSNMEAL SLSTLRIHEE SRGDGVVINI PDLRKKCIFN SKTIHEKKKF YNVNSINADK
NAEVISSTHD ARVLMDATTF SRLLVGKWGC DNLDYSFPIN VAQEFVDGGL ENIVTISKPV
PSSPPSTRTL AYKFMKYVVK SAVDKSYFNV PKEVVNDSQN ESETNDFAPS SPFFPTSPTR
ANDDSTQNIV EHTNEKKADS DSNYHRGKIY HILNLNTGTS DPNFNILVRS NCAEKDCFGK
RLSVSHHVEY FPEIGAENLF PEEIVRNYIK CFFKGANHAA IFRVHNSSYN VLQKEFIDLH
TLQNRVYSEC LHIWKNGLQK VRNILMKLMT VSGGEYLLEE DDNSFKLFSK TIPIEDDTEN
VQMELRKALQ RSNQEDDMIR SGALNSSGIF NGVSYHVPLM WNFVLSRIPG SLPKRKKNVN
QDTFHSNKGK HKKKFINN
//
