ID   A0A0K0FXC2_STRVS        Unreviewed;       657 AA.
AC   A0A0K0FXC2;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Integrase catalytic domain-containing protein {ECO:0000313|WBParaSite:SVE_1709800.1};
OS   Strongyloides venezuelensis (Threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=75913 {ECO:0000313|Proteomes:UP000035680, ECO:0000313|WBParaSite:SVE_1709800.1};
RN   [1] {ECO:0000313|Proteomes:UP000035680}
RP   NUCLEOTIDE SEQUENCE.
RA   Martin A.A, De Silva N.;
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:SVE_1709800.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (AUG-2015) to UniProtKB.
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DR   AlphaFoldDB; A0A0K0FXC2; -.
DR   STRING; 75913.A0A0K0FXC2; -.
DR   WBParaSite; SVE_1709800.1; SVE_1709800.1; SVE_1709800.
DR   Proteomes; UP000035680; Unassembled WGS sequence.
DR   GO; GO:0042575; C:DNA polymerase complex; IEA:UniProt.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041577; RT_RNaseH_2.
DR   PANTHER; PTHR33064; POL PROTEIN; 1.
DR   PANTHER; PTHR33064:SF36; RT_RNASEH_2 DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   Pfam; PF17919; RT_RNaseH_2; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000035680}.
FT   DOMAIN          498..657
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
SQ   SEQUENCE   657 AA;  75536 MW;  C0F75AC4604F0437 CRC64;
     MCKTNFQIKD DLRDDDSSNK MDDSTCIELN VSENENSKLD LKSNNLSILC NMALYENKNS
     IYHEEISKRF SYILCNHKFD VGPGILKVPD QVIIENVDIK KNVRFPSRTD KENETINSYI
     EQMVNANILE KGHVPKPGAT EDLRVVADLR SINAQTVPFN YESELTREMF ARLSQAKKKR
     PNGCYFFKRL PQSAKNNSML FNATLENLLL PFKDNVLLYC DDIVIYSNEN DNHFEIVMSI
     LNKFSEAFLR INISKYISPS EESLKRFKKR RKPINIKELI SLLLSCNYFK GNIHKFVDLS
     QPLMEICPSK GSKRIEWNPT LDKQYEALVE AVQIAEIIYY PGYSLPFYIT SDACQHGIGA
     YLSQFHGNSE KIIGYFSKKI DSTVKARNPT FTEAISLREA IYYFKPITRG HLTFLKTDHK
     NLVNIVKNGN NPRYGTFIEA VESGNSKICY INALNNPVAD DLSRHGVVNT IIDENLLPKR
     ILTKEIYPTI VLDDKAVNYS KPNECIAIGI CGKISPASNT YCYVLGIINC FSRFVTLIPL
     KRYDYSSVSK ALFHQYFYIH GLPSQVYVDG GGNFKNKKLK KMMVDMKVNL TNTIPYYSKS
     NTIIERMFKQ MLNCIAKYDG EWSELLPACA YYHNVMEHSI IEKSSYYLHF PRKPLLI
//