ID A0A0K0G4W4_STRVS Unreviewed; 881 AA.
AC A0A0K0G4W4;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=SSD domain-containing protein {ECO:0000313|WBParaSite:SVE_1977600.1};
OS Strongyloides venezuelensis (Threadworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=75913 {ECO:0000313|Proteomes:UP000035680, ECO:0000313|WBParaSite:SVE_1977600.1};
RN [1] {ECO:0000313|Proteomes:UP000035680}
RP NUCLEOTIDE SEQUENCE.
RA Martin A.A, De Silva N.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:SVE_1977600.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (AUG-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the patched family.
CC {ECO:0000256|ARBA:ARBA00005585}.
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DR AlphaFoldDB; A0A0K0G4W4; -.
DR WBParaSite; SVE_1977600.1; SVE_1977600.1; SVE_1977600.
DR Proteomes; UP000035680; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR PANTHER; PTHR10796:SF112; SSD DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02460; Patched; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000035680};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 469..490
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 683..712
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 732..753
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 774..800
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 806..831
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 255..412
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 881 AA; 99918 MW; 4A83E47A8BD22456 CRC64;
MRPLVWLENT IKSGFFRLGL WIYDNHYLCF FGSIILAFIL GVGAKNFREV NNVRDHFSAE
DSPSRREFAI ARDFFKDYGK PFTLVVAIQS QDDGDILRPG YIDRAMEIEN FLQYQLNVTY
NGKSYAYSDF CGAQCETSDA VSIFLTMYRD SKHRKTNNVK LTYPSMDVFG HTVYLANNIF
KVQTSEKSKL IKSVGLISIN FNAIYSNETM GKIMSLWEHA VLDFSLSSVN DPYIKVFTTS
EGLVSEEIRR TGVQAAPLMS VSFLVVLIFT ILCSLDKDVV KSKPWEAFFG VICPPLSLMA
SFGTLFWFNY EFIPIVTVVP FLIMAIGVDD VFIFLHSYRN TDENLPVREK IAHMLADAGP
SITITSLTNL LSFGIGICTP TPAIKIFCVF VTVSVIYDYI YQIFFFTAIL VFGGHREERN
GHGYYWFVNV KNYDKKNGAI KEKCTLERKI GELIDNFVDY WVTFSMSTAA RVLIVIVLIV
FWSFSIYGVL QIKVGLTSEK LFLDDSPLLP LVRIQNNIIF KEGGQMIVFV NNPGNLSNPD
SITEIMKILN KFETSLRSVG PSSSQMWLNA YLPFIGLQNR GSIDFKYKYL PEFFSLTEYH
KWSHFVSIGN TSDCYIEHPN CIHKFFFSTG FANAIAWTER LELLQHWRAL AEEFPQFNLT
IYEDFSLYAD QLLSIPPVTQ QTVFYALLCM TIVLVCFTPN ISTIISGVAS IMSINLGVFG
LLHFCSIDLD PISMATTLMA IGFSVDFIAH ISFHYYKGDH EDRRERLIHA LKSIAMPMVQ
AGSSTILSIL VLALIHAYMV QVFVKVVTLV VGLGMIHGLI VLPIVYAALP FQKEINVEEK
KDLKKVVPVN DNISIHSIKK VAPIEDGLNY TPTTERYSNT K
//
