ID A0A0K0J596_BRUMA Unreviewed; 331 AA.
AC A0A0K0J596; A0A0H5S9C8;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 3.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=BMA-OSTA-2 {ECO:0000313|EMBL:CRZ24735.1, ECO:0000313|WBParaSite:Bm2286.1};
GN Name=bma-osta-2 {ECO:0000313|WormBase:Bm2286};
GN Synonyms=Bma-osta-2 {ECO:0000313|EMBL:CRZ24735.1};
GN ORFNames=Bm2286 {ECO:0000313|WormBase:Bm2286}, BM_Bm2286
GN {ECO:0000313|EMBL:CRZ24735.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CRZ24735.1};
RN [1] {ECO:0000313|EMBL:CRZ24735.1, ECO:0000313|Proteomes:UP000006672}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ24735.1,
RC ECO:0000313|Proteomes:UP000006672};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CRZ24735.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ24735.1};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:Bm2286.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2022) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; LN856984; CRZ24735.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0K0J596; -.
DR EnsemblMetazoa; Bm2286.1; Bm2286.1; WBGene00222547.
DR WBParaSite; Bm2286.1; Bm2286.1; WBGene00222547.
DR WormBase; Bm2286; BM23770; WBGene00222547; Bma-osta-2.
DR OMA; MEAFCVT; -.
DR OrthoDB; 2877401at2759; -.
DR Proteomes; UP000006672; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR005178; Ostalpha/TMEM184C.
DR PANTHER; PTHR23423:SF76; ORGANIC SOLUTE TRANSPORTER ALPHA-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR23423; ORGANIC SOLUTE TRANSPORTER-RELATED; 1.
DR Pfam; PF03619; Solute_trans_a; 1.
DR SMART; SM01417; Solute_trans_a; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006672};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 331 AA; 37527 MW; 782FD0380134EC5F CRC64;
MFHTVLKLVA DSLLNCTDGP TGIVSARVYL SRIEVTFIVT LLGSTLISLA TACLGVLHVI
YISFYVTQRY RRAFIVYLAG TAPFVSTLSL VAMYMPRVWF LSHLLGFLYF SIALWVIICL
LMNIFEGRQK MVRKMKSGCS RISVQTPPLC CVFPCLPKLE LDQGRIRFCE MMVFQAPCIR
LIFTILSLIL YFEYQDGAII ALKILDFISL PSLLIGVYGT HILVTTVSNL DELILYRYIV
VFRLLDFYFM FYGIQQPVFD FLARSGVFGC GTVLPSLETA FFWKNFIVVI ESFFVSLIST
ILLKPSRSAF FDKYPSSRSV ASSVVTCEYS T
//
