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Database: UniProt
Entry: A0A0K0TXR4_9RHIZ
LinkDB: A0A0K0TXR4_9RHIZ
Original site: A0A0K0TXR4_9RHIZ 
ID   A0A0K0TXR4_9RHIZ        Unreviewed;       357 AA.
AC   A0A0K0TXR4;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   08-MAY-2019, entry version 16.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   Name=DAHP_synth_1 {ECO:0000313|EMBL:AKR56543.1};
GN   ORFNames=XM25_12205 {ECO:0000313|EMBL:AKR56543.1};
OS   Devosia sp. H5989.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Hyphomicrobiaceae; Devosia.
OX   NCBI_TaxID=1643450 {ECO:0000313|EMBL:AKR56543.1, ECO:0000313|Proteomes:UP000037066};
RN   [1] {ECO:0000313|EMBL:AKR56543.1, ECO:0000313|Proteomes:UP000037066}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H5989 {ECO:0000313|EMBL:AKR56543.1,
RC   ECO:0000313|Proteomes:UP000037066};
RX   PubMed=26337876;
RA   Nicholson A.C., Whitney A.M., Humrighouse B., Emery B., Loparev V.,
RA   McQuiston J.R.;
RT   "Complete Genome Sequence of Strain H5989 of a Novel Devosia
RT   Species.";
RL   Genome 3:e00934-15(2015).
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; CP011300; AKR56543.1; -; Genomic_DNA.
DR   RefSeq; WP_049706086.1; NZ_CP011300.1.
DR   EnsemblBacteria; AKR56543; AKR56543; XM25_12205.
DR   KEGG; deq:XM25_12205; -.
DR   PATRIC; fig|1643450.3.peg.2478; -.
DR   KO; K01626; -.
DR   OrthoDB; 853329at2; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000037066; Chromosome.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000037066};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037066};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       44    338       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   357 AA;  38939 MW;  775E7F4C7F5CB75E CRC64;
     MLKSTDDLRI RELRELSTPA EVIREYPRTE GATRTVTGSR LALHNILAGR DDRLAVVIGP
     CSIHDPEAAL DYAARLWELR RRLAGSLEIV MRVYFEKPRT TVGWKGLIND PDLDGSFQID
     KGLRRARSLL LEINDMGLPA GCEFLDMTTP QYFADLVAWG AIGARTTESQ VHRELASGLS
     CPVGFKNGTD GNVRIALDAV KSATQPHHFL AVTKDGRSAI ATTTGNEDCH IILRGGKATN
     YDAASVEAAA AESRKAGIRP AIMIDASHAN SSKKPENQPL VMEDVARQLE AGDNRIMGVM
     VESNLVAGRQ DLVPGKPLIY GQSITDGCID WDTTVTVLER LAKATETRRQ VSKQEVA
//
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