ID A0A0K1EQ44_CHOCO Unreviewed; 756 AA.
AC A0A0K1EQ44;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=CMC5_072720 {ECO:0000313|EMBL:AKT43045.1};
OS Chondromyces crocatus.
OC Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae;
OC Chondromyces.
OX NCBI_TaxID=52 {ECO:0000313|EMBL:AKT43045.1, ECO:0000313|Proteomes:UP000067626};
RN [1] {ECO:0000313|EMBL:AKT43045.1, ECO:0000313|Proteomes:UP000067626}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Cm c5 {ECO:0000313|EMBL:AKT43045.1,
RC ECO:0000313|Proteomes:UP000067626};
RA Zaburannyi N., Bunk B., Maier J., Overmann J., Mueller R.;
RT "Genome analysis of myxobacterium Chondromyces crocatus Cm c5 reveals a
RT high potential for natural compound synthesis and the genetic basis for the
RT loss of fruiting body formation.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP012159; AKT43045.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0K1EQ44; -.
DR STRING; 52.CMC5_072720; -.
DR KEGG; ccro:CMC5_072720; -.
DR PATRIC; fig|52.7.peg.7989; -.
DR OrthoDB; 5479234at2; -.
DR Proteomes; UP000067626; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000067626}.
FT DOMAIN 53..123
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 125..177
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 535..751
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 756 AA; 82248 MW; 5CCBB31C82C98CF8 CRC64;
MPAARRIPLE RGVLTHERML PSPLNCAFGW KVRREACVRE AGSGGDGALV SSDGELLRQI
AEMSPLLICY VDRDQRYRMV NRAYEGWFGV APEELIGHHV RDVVGEQAYA PLKRPIEAAL
SGERITLETK LLYRKGGLRY VRVNYVPHRS DEGEILGYLA LIEDLSERQR LEEIRRFLAE
ATAILASSLD YMDSWQRVAR LATSTVADWC WIHDLAPDGT LRLVHVEHAD TDMTDRARTQ
GDPHRARVTA PSPFHDILEG RSAGFVTQDL QSLAAGQATA DAEHLAYLLS LKHRSTITVP
IPGQGKIIGA LTLASSEPGR FDGGDDRSIT EELARRLGLA EQHARALQAE QEARLAAERA
TRRMSLLQHI TAALANAITA EEVADVVLTH GLPAAGLRGG AVLLTAEGGA ALEVLRSQGY
PPGVLEAGQR VPIPVDEGGA LAALAAAGSL LPLDVGARHH GYLAIGLDAT RPLPAEDHQL
HVAIATQCAQ ALERARLHQE RAELHDHAQR IAAENAALYQ EARESEERKD EFLAMLCHEL
RNPLTPMLMG LELLRRGLRN NDLDRNAAII QRQAETIARL VEDLLDISRI TRGKIELRRH
PLDVASVMAS AVETARPLVE SRQHALTIEA PEGLQIEADW VRIEQVLTNL LNNAAKYTDP
GGNIALSAAR DGGNVVLSVR DTGLGIPADA LPHIFEPFMQ AERSLDHALG GLGIGLTLVK
RLVELHGGHV EALSEGAGMG TEVRVRIPLT AAALPS
//
