ID   A0A0K1JW98_9BURK        Unreviewed;       380 AA.
AC   A0A0K1JW98;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE            EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN   ORFNames=ACZ75_07725 {ECO:0000313|EMBL:AKU21387.1};
OS   Massilia sp. NR 4-1.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Oxalobacteraceae; Telluria group; Massilia.
OX   NCBI_TaxID=1678028 {ECO:0000313|EMBL:AKU21387.1, ECO:0000313|Proteomes:UP000056897};
RN   [1] {ECO:0000313|EMBL:AKU21387.1, ECO:0000313|Proteomes:UP000056897}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NR 4-1 {ECO:0000313|EMBL:AKU21387.1,
RC   ECO:0000313|Proteomes:UP000056897};
RA   Sul W.J.;
RT   "Massilia sp. NR 4-1 isolated from rhizosphere of Torreya nucifera in
RT   national heritage Bijarim forest, volcanic Jeju Island, Korea.";
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC         methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC         ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00001709};
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DR   EMBL; CP012201; AKU21387.1; -; Genomic_DNA.
DR   RefSeq; WP_050408200.1; NZ_CP012201.1.
DR   AlphaFoldDB; A0A0K1JW98; -.
DR   STRING; 1678028.ACZ75_07725; -.
DR   KEGG; mnr:ACZ75_07725; -.
DR   PATRIC; fig|1678028.3.peg.1583; -.
DR   OrthoDB; 9790967at2; -.
DR   Proteomes; UP000056897; Chromosome.
DR   GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR   CDD; cd06558; crotonase-like; 1.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR045004; ECH_dom.
DR   InterPro; IPR032259; HIBYL-CoA-H.
DR   PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR   Pfam; PF16113; ECH_2; 1.
DR   SUPFAM; SSF52096; ClpP/crotonase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000056897}.
FT   DOMAIN          19..363
FT                   /note="Enoyl-CoA hydratase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF16113"
SQ   SEQUENCE   380 AA;  40568 MW;  28E30482C3A46386 CRC64;
     MSAAVLFEEL PAGGGKRLGV ATLNAEKSLN SLSLEMVHAL TERLTVWADD DGIAVVLLQA
     AGEKAFCAGG DLQNLYTSMR QHHSSPEHGN AAANQYAADF FRHEYRLDYQ IHTYPKPVLC
     WGHGIVMGGG IGLMAGASHR VVTGQSRLAM PEISIGLFPD VGGSWLLSRM PGKTGLFLAL
     TGAQVRAADA LFLGLADHGI AQENKAAVLA TLLEQPWSGQ RADNDRLLTQ LLRRHADPAL
     AEAGPVRQHF EAINRLCGAA SLAQIVAALS QHASDDAWFN KAIATLRAGS PGSIALSHAL
     QQRVAGLSLA DVFRLEYIAA LHCAARPDFA EGIRALLIDK DGKPGWQPPT LQQVSADWLE
     GFFTAPAWPA HPLADLGRPL
//