ID A0A0K1NEP6_9BURK Unreviewed; 516 AA.
AC A0A0K1NEP6;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Acetyl-CoA hydrolase {ECO:0000313|EMBL:AKU67582.1};
GN ORFNames=ADJ79_10775 {ECO:0000313|EMBL:AKU67582.1};
OS Ottowia sp. oral taxon 894.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Ottowia.
OX NCBI_TaxID=1658672 {ECO:0000313|EMBL:AKU67582.1, ECO:0000313|Proteomes:UP000056623};
RN [1] {ECO:0000313|Proteomes:UP000056623}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W10237 {ECO:0000313|Proteomes:UP000056623};
RA Holder M.E., Ajami N.J., Petrosino J.F.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
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DR EMBL; CP012073; AKU67582.1; -; Genomic_DNA.
DR RefSeq; WP_050715949.1; NZ_CP012073.1.
DR AlphaFoldDB; A0A0K1NEP6; -.
DR STRING; 1658672.ADJ79_10775; -.
DR KEGG; oto:ADJ79_10775; -.
DR PATRIC; fig|1658672.3.peg.2704; -.
DR OrthoDB; 9801795at2; -.
DR Proteomes; UP000056623; Chromosome.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR017821; Succinate_CoA_transferase.
DR NCBIfam; TIGR03458; YgfH_subfam; 1.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:AKU67582.1}.
FT DOMAIN 21..230
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 336..478
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
FT ACT_SITE 303
FT /note="5-glutamyl coenzyme A thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-1"
FT BINDING 373
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 393
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 397
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 417
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
SQ SEQUENCE 516 AA; 56232 MW; E02421CA264633CE CRC64;
MNTQAFTPEA TQARIQHEGL RSKIMTAEQA AELIQPGFNV GMSGFTGSGY PKAVPLALAA
RMEAAHAAGK PFRVGLWTGA STAPELDGAL AKAEGISMRL PYQSDPTVRN QINAGGMFYS
DMHLSHVAPM AWAGFFGRLN VAVIEVAGIL PDGRLIPTTS VGNNKTWLDI ADHVILEVNH
WQSTGLEGMH DIYYGTRLPP HRQPIMLTAP HDRIGEPYLH CDPEKIIAIV QTDAHDRNSP
FSPPDENSRL IAQHMIDFFQ HEVKAGRLPA NLLPLQSGVG NIANAVLAGL NESPFNNMTA
YTEVLQDGML EMIKSGKLTF ASATALSLSP EATQYFTTHL DEFRGRVLLR PQEISNHPEL
IRRMGMLAMN AMIEADIYGN VNSTHLMGST VMNGIGGSGD FARNAYISFF MSPSTAKGGA
ISCIVPMVSH TDHTEHDVQV IVTEQGLADL RGLAPVPRAR RVIEKCAHPD YRDALTDYLD
RALAGGAPGK HTPHLLQESL SWHQRFVQTG DMRKKG
//
