ID A0A0K1RLR5_9CIRC Unreviewed; 272 AA.
AC A0A0K1RLR5;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 08-NOV-2023, entry version 24.
DE RecName: Full=Replication-associated protein {ECO:0000256|ARBA:ARBA00014531};
DE AltName: Full=ATP-dependent helicase Rep {ECO:0000256|ARBA:ARBA00030754};
DE AltName: Full=RepP {ECO:0000256|ARBA:ARBA00032243};
OS Calanoida sp. copepod associated circular virus.
OC Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes;
OC Cirlivirales; Circoviridae.
OX NCBI_TaxID=1692244 {ECO:0000313|EMBL:AKV62292.1, ECO:0000313|Proteomes:UP000169232};
RN [1] {ECO:0000313|EMBL:AKV62292.1, ECO:0000313|Proteomes:UP000169232}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=I0298 {ECO:0000313|EMBL:AKV62292.1};
RX PubMed=26217327; DOI=10.3389/fmicb.2015.00696;
RA Rosario K., Schenck R.O., Harbeitner R.C., Lawler S.N., Breitbart M.;
RT "Novel circular single-stranded DNA viruses identified in marine
RT invertebrates reveal high sequence diversity and consistent predicted
RT intrinsic disorder patterns within putative structural proteins.";
RL Front. Microbiol. 6:696-696(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001836};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000256|ARBA:ARBA00004147}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the nanoviruses/circoviruses replication-
CC associated protein family. {ECO:0000256|ARBA:ARBA00008545}.
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DR EMBL; KR528563; AKV62292.1; -; Genomic_DNA.
DR RefSeq; YP_009163927.1; NC_027795.1.
DR GeneID; 25479235; -.
DR KEGG; vg:25479235; -.
DR OrthoDB; 9195at10239; -.
DR Proteomes; UP000169232; Genome.
DR GO; GO:0016888; F:endodeoxyribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR Gene3D; 3.40.1310.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000605; Helicase_SF3_ssDNA/RNA_vir.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003365; Viral_rep_N.
DR Pfam; PF00910; RNA_helicase; 1.
DR Pfam; PF02407; Viral_Rep; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Host nucleus {ECO:0000256|ARBA:ARBA00022562};
KW Reference proteome {ECO:0000313|Proteomes:UP000169232}.
FT DOMAIN 7..86
FT /note="Viral replication-associated protein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02407"
FT DOMAIN 157..239
FT /note="Helicase superfamily 3 single-stranded DNA/RNA
FT virus"
FT /evidence="ECO:0000259|Pfam:PF00910"
SQ SEQUENCE 272 AA; 31258 MW; 527C7C26A4409C52 CRC64;
MVNSGKHWCF TLNNYTPEEE SSIKLVDAVY LVYGRERGES DTPHLQGFVS FDKRRTLRQV
KELLSDRVHL ESAKGTPRQA SEYCKKDGDY YEVGILPGGR GTRTDLESVR ELIKSGGSIR
DVFDKHFGVA LRYHRGISMA INLRGDKREW VVDVQVYWGD TGSGKTKKAW TEAPDAYVHP
GGQWFDGYTG QPDVIFDDFS GSEFKLTYLL KLLDRYPMQV PVKGGFVNWV PKRIFITSNL
DPRTWYKDAI QEHQAALMRR ITKITHFTIP FH
//
