ID A0A0K2AP17_STRA7 Unreviewed; 871 AA.
AC A0A0K2AP17;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Glycine/betaine ABC transporter permease {ECO:0000313|EMBL:AKZ54724.1};
GN ORFNames=SAM23877_1675 {ECO:0000313|EMBL:AKZ54724.1};
OS Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 /
OS NBRC 12836 / NRRL B-2516).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=278992 {ECO:0000313|EMBL:AKZ54724.1, ECO:0000313|Proteomes:UP000061018};
RN [1] {ECO:0000313|Proteomes:UP000061018}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL
RC B-2516 {ECO:0000313|Proteomes:UP000061018};
RX PubMed=26410452; DOI=10.1016/j.jbiotec.2015.09.020;
RA Thibessard A., Haas D., Gerbaud C., Aigle B., Lautru S., Pernodet J.L.,
RA Leblond P.;
RT "Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the
RT spiramycin producer.";
RL J. Biotechnol. 214:117-118(2015).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363032};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363032}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. {ECO:0000256|RuleBase:RU363032}.
CC -!- SIMILARITY: In the C-terminal section; belongs to the OsmX family.
CC {ECO:0000256|ARBA:ARBA00035642}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the binding-protein-
CC dependent transport system permease family.
CC {ECO:0000256|ARBA:ARBA00035652}.
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DR EMBL; CP012382; AKZ54724.1; -; Genomic_DNA.
DR RefSeq; WP_053128265.1; NZ_CP012382.1.
DR AlphaFoldDB; A0A0K2AP17; -.
DR STRING; 1889.SAM40697_1497; -.
DR KEGG; samb:SAM23877_1675; -.
DR Proteomes; UP000061018; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR CDD; cd13639; PBP2_OpuAC_like; 2.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; MetI-like; 1.
DR InterPro; IPR007210; ABC_Gly_betaine_transp_sub-bd.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR PANTHER; PTHR47737; GLYCINE BETAINE/PROLINE BETAINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW; 1.
DR PANTHER; PTHR47737:SF1; GLYCINE BETAINE_PROLINE BETAINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR Pfam; PF04069; OpuAC; 2.
DR SUPFAM; SSF161098; MetI-like; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 2.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363032};
KW Reference proteome {ECO:0000313|Proteomes:UP000061018};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363032};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363032};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363032}.
FT TRANSMEM 49..79
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 91..114
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 134..162
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 201..227
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 239..262
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 301..320
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT DOMAIN 87..266
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50928"
SQ SEQUENCE 871 AA; 95004 MW; 6B175AF86E03AEDA CRC64;
MPRIPLGDWV NEAVDWLLGH VAWLFDFLKT VFTGTYDGIN AVLQAPEPLL LVGIFAIIAF
WLRGTVAGVL TFLGFAFIIS MELWENAMIT LALVLVATII ALVIAVPVGI WAARSDRVSG
LVRPVLDFMQ TLPAMIYLIP AILFFGTGAS AGIVATLIFA LAPGVRMTEL GIRQVDKELV
EAAEAFGTTP RNTLLRVQLP LALPTVMAGV NQVIMLGLSM AAIAGMVGTG GLGGDVNEAI
GQLNVGLGSE AGVAIVILAI YLDRMTSALG TQVSPLGRRA AAKARAAGGL KIWSYRPRPQ
VAVIGVVILA LVAGGMGMFG GSGDSESVAD GKNVGQGKKV TLGYVPWDEG VASTFLWKEM
LEQRGYEVEA KQFDAGPLYT SLAQGDIDVV TNSWLPTTHE QYWKKYGDRL DDLGSWYDET
SLELTVPAYM KDINSLADLK GKAGLFKGKI TGIESSAGEM ALLKDKVAKE YGLDEEYKVV
DSSTPAMLAE LKRAMSKKEP IVVTLWSPHW AYNDLDLKKL KDPKGAWGEG DGVHTLSRKG
FAGDDPTAAK WLKDFKLTEQ QLTSLEAEIN KAGKGKQQDA VRTWLKSNPG LVDKLAPVEG
GAGGTPAEAK RTLDVAWFPW EEDVAVTYLW KNVLERRGYK MNLKQMDVGP VYTGLASGDL
DLNFDAWLPH AQKNYWEKNK DNLTDLGTWY EPTSLEIAVP SYVKDVKSLA DLKGKADLFD
GKIIGIEPGT GEMQLAKDEV LPGYGLEDEY EIVDGSTPAM LAELKRAYAK KEPVAVTLWS
PHWAYSDYEL TKLKDPKKAF GEGNTIRTIS SKKFPEQYPQ LTKWIKGFHM SEDELGTLEA
EIKDRGQGHE EEAVAAWLKE HPEMVDRMTP Q
//
