ID A0A0K2ARZ2_STRA7 Unreviewed; 424 AA.
AC A0A0K2ARZ2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Deoxyguanosinetriphosphate triphosphohydrolase-like protein {ECO:0000256|HAMAP-Rule:MF_01212};
GN ORFNames=SAM23877_2523 {ECO:0000313|EMBL:AKZ55572.1};
OS Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 /
OS NBRC 12836 / NRRL B-2516).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=278992 {ECO:0000313|EMBL:AKZ55572.1, ECO:0000313|Proteomes:UP000061018};
RN [1] {ECO:0000313|Proteomes:UP000061018}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL
RC B-2516 {ECO:0000313|Proteomes:UP000061018};
RX PubMed=26410452; DOI=10.1016/j.jbiotec.2015.09.020;
RA Thibessard A., Haas D., Gerbaud C., Aigle B., Lautru S., Pernodet J.L.,
RA Leblond P.;
RT "Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the
RT spiramycin producer.";
RL J. Biotechnol. 214:117-118(2015).
CC -!- SIMILARITY: Belongs to the dGTPase family. Type 2 subfamily.
CC {ECO:0000256|HAMAP-Rule:MF_01212}.
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DR EMBL; CP012382; AKZ55572.1; -; Genomic_DNA.
DR RefSeq; WP_053130408.1; NZ_CP012382.1.
DR AlphaFoldDB; A0A0K2ARZ2; -.
DR STRING; 1889.SAM40697_2319; -.
DR KEGG; samb:SAM23877_2523; -.
DR Proteomes; UP000061018; Chromosome.
DR GO; GO:0016793; F:triphosphoric monoester hydrolase activity; IEA:InterPro.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR HAMAP; MF_01212; dGTPase_type2; 1.
DR InterPro; IPR006261; dNTPase.
DR InterPro; IPR023023; dNTPase_2.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR026875; PHydrolase_assoc_dom.
DR NCBIfam; TIGR01353; dGTP_triPase; 1.
DR PANTHER; PTHR11373:SF32; DEOXYGUANOSINETRIPHOSPHATE TRIPHOSPHOHYDROLASE; 1.
DR PANTHER; PTHR11373; DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF13286; HD_assoc; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|HAMAP-Rule:MF_01212, ECO:0000313|EMBL:AKZ55572.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000061018}.
FT DOMAIN 70..220
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 424 AA; 46113 MW; 65E92E6A5EB07599 CRC64;
MEGTAPPPPY DPTSVARYAP EPDKRPGRTA FQRDRARILH SGALRRLAGK TQVVTPGEGS
PVWDASPRTR LTHSLECAQV GRELGAALGC DPDLVEAACL SHDLGHPPFG HNGEQALNAF
AEDCGGFEGN AQSLRLLTRL EPKRFTEDGS VGLNLTRAAL DAATKYPWPR GAHPTDPGSP
KFGVYDDDRP VFEWLRKDAP GSRTCFEAQV MDWADDVAYS VHDVEDGLHA GHIDPNCLLA
DPEREAVFEA AVGRYVPAGT DHAELAAALD RLLAQDWWPH GYDGSAVAQA RLKDATSQLI
GRFCLAAESA TRAAYGSGRL TRYTAELVVP RGTRLECAVL KAVAVRYVMQ RTEQERLRAD
QRVVVAELAQ ALTARAPDGL DPQFRALFDR APDDRARKRV IVDQIASLTD ASARSLHARL
TGHP
//
