ID   A0A0K2B057_STRA7        Unreviewed;      1016 AA.
AC   A0A0K2B057;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=N-acetyltransferase domain-containing protein {ECO:0000259|PROSITE:PS51186};
GN   ORFNames=SAM23877_5548 {ECO:0000313|EMBL:AKZ58593.1};
OS   Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 /
OS   NBRC 12836 / NRRL B-2516).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=278992 {ECO:0000313|EMBL:AKZ58593.1, ECO:0000313|Proteomes:UP000061018};
RN   [1] {ECO:0000313|Proteomes:UP000061018}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL
RC   B-2516 {ECO:0000313|Proteomes:UP000061018};
RX   PubMed=26410452; DOI=10.1016/j.jbiotec.2015.09.020;
RA   Thibessard A., Haas D., Gerbaud C., Aigle B., Lautru S., Pernodet J.L.,
RA   Leblond P.;
RT   "Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the
RT   spiramycin producer.";
RL   J. Biotechnol. 214:117-118(2015).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP012382; AKZ58593.1; -; Genomic_DNA.
DR   RefSeq; WP_053138277.1; NZ_CP012382.1.
DR   AlphaFoldDB; A0A0K2B057; -.
DR   STRING; 1889.SAM40697_5032; -.
DR   KEGG; samb:SAM23877_5548; -.
DR   Proteomes; UP000061018; Chromosome.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   CDD; cd04301; NAT_SF; 1.
DR   Gene3D; 3.40.630.30; -; 1.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR003781; CoA-bd.
DR   InterPro; IPR000182; GNAT_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR032875; Succ_CoA_lig_flav_dom.
DR   InterPro; IPR016102; Succinyl-CoA_synth-like.
DR   PANTHER; PTHR42793; COA BINDING DOMAIN CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR42793:SF1; PEPTIDYL-LYSINE N-ACETYLTRANSFERASE PATZ; 1.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   Pfam; PF13549; ATP-grasp_5; 1.
DR   Pfam; PF13380; CoA_binding_2; 1.
DR   Pfam; PF13607; Succ_CoA_lig; 1.
DR   SMART; SM00881; CoA_binding; 1.
DR   SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
DR   PROSITE; PS51186; GNAT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000061018}.
FT   DOMAIN          26..185
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS51186"
FT   REGION          621..725
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        670..707
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1016 AA;  106576 MW;  8D570D20542A6FDE CRC64;
     MQTSSDRHEY PAHWEADVVL RDGGTARVRP ITVDDAERLV SFYEQVSDES KYYRFFAPYP
     RLSAKDVHRF THHDFVDRVG LAATIGGEFI ATVRYDRIGA GGTPASAPAD EAEVAFLVQD
     AHQGRGVASA LLEHIAAVAR ERGIRRFAAE VLPANTKMIK VFMDAGYTQK RSFEDGVVRL
     EFDLEPTDRS LAVQYAREHR AEARSVQRLL QPGSVAVIGT GRTPGGVGRS ILGNIRDAGY
     TGRLYAVNRA FPEGRDTLDG VPARRSVRDI DGPVDLAVVT VPAEHVPDVV TECGEHGVQG
     LVVVSAGYAD SGPEGRERQR ALVRQARTYG MRIIGPNAFG VINTSPDVRL NASLAPEMPR
     PGRIGLFAQS GAIGIALLSR LHRRGGGVTG VTGVSTFVSS GNRADVSGND VLQYWYDDPQ
     TDVALMYLES IGNPRKFTRL ARRTAAVKPL VVVQGARHGG VAPQGHAVRA TRLPHATVSA
     LLRQAGVIRV DTITDLVDAG LLLARQPLPA GPRVAILGNS ESLGLLTYDA CLSEGLRPHP
     PLDLTTAASA DEFHAALSRA LADDTCDAVV VTAIPAVGEG SAGDAALAEA LRSAAAAVPA
     KPVLVVHVEL GGLAEALSAA ASTAPQPPPP ADPQAVAPAT PHAASPPDQQ AAPSTAEDRA
     ASAGPGASAP SEPRTPPLSE PRTPPPAGPR TGSPDGSRTP PPPSPATASA SGSTRHSPAA
     DEPAEAPEGL HLIPAYPAAE RGVRALAQAV AYAQWRRDAA DPGKVPEYED IDEKGAAALI
     AGHLARGQGL TLGTEETCEL LGRYGIRVHR AMPAPTPDDA AAAARTLGYP VALKATAPHL
     RHRADLGGVR LDLADEEQLR RAYAELTELF GTPAELRPVV QGMAPRGVDT VVRAVIDPAA
     GAALSFGLAG AATQLLGDMA HRLIPVTDRE AGSLIRSIRT APLLFGWRGS APVDSAALEE
     LLLRVSRLVD DHPEVVAVTL EPVVVAPRGL SVLSASVRLA PPPARDDLGP RTLPAY
//