ID A0A0K2QQW5_9CAUD Unreviewed; 242 AA.
AC A0A0K2QQW5;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 2.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=dTMP kinase {ECO:0000256|ARBA:ARBA00012980};
DE EC=2.7.4.9 {ECO:0000256|ARBA:ARBA00012980};
OS Ralstonia phage RSF1.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Chiangmaivirus; Chiangmaivirus RSF1.
OX NCBI_TaxID=1689679 {ECO:0000313|EMBL:BAS04984.2, ECO:0000313|Proteomes:UP000202583};
RN [1] {ECO:0000313|EMBL:BAS04984.2, ECO:0000313|Proteomes:UP000202583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RSF1 {ECO:0000313|EMBL:BAS04984.2,
RC ECO:0000313|Proteomes:UP000202583};
RA Kawasaki T., Fujie M., Chatchawankanphanich O., Ogata H., Yamada T.;
RT "Two Asian jumbo phage RSL2 and RSF1 infecting the phytopathogen Ralstonia
RT solanacearum share common features related to the phi-KZ-like phages.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + dTMP = ADP + dTDP; Xref=Rhea:RHEA:13517,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58369, ChEBI:CHEBI:63528,
CC ChEBI:CHEBI:456216; EC=2.7.4.9;
CC Evidence={ECO:0000256|ARBA:ARBA00001008};
CC -!- SIMILARITY: Belongs to the thymidylate kinase family.
CC {ECO:0000256|ARBA:ARBA00009776}.
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DR EMBL; AP014927; BAS04984.2; -; Genomic_DNA.
DR RefSeq; YP_009207996.1; NC_028899.1.
DR GeneID; 26634653; -.
DR KEGG; vg:26634653; -.
DR OrthoDB; 14971at10239; -.
DR UniPathway; UPA00575; -.
DR Proteomes; UP000202583; Genome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004798; F:thymidylate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006233; P:dTDP biosynthetic process; IEA:InterPro.
DR GO; GO:0006235; P:dTTP biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd01672; TMPK; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00165; Thymidylate_kinase; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039430; Thymidylate_kin-like_dom.
DR InterPro; IPR018094; Thymidylate_kinase.
DR PANTHER; PTHR10344; THYMIDYLATE KINASE; 1.
DR PANTHER; PTHR10344:SF4; THYMIDYLATE KINASE; 1.
DR Pfam; PF02223; Thymidylate_kin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000202583}.
FT DOMAIN 20..122
FT /note="Thymidylate kinase-like"
FT /evidence="ECO:0000259|Pfam:PF02223"
SQ SEQUENCE 242 AA; 27672 MW; B3E69B2E0F7B6561 CRC64;
MAFFPDAKEI GANQNRFWTI EGIDGSGKSS ISQFISDYLS KKGIPNTLVA AYPKDEEASF
MRDAWIHQRI PMPAVLSCIL YLRRRVLTES IIPALLAGQV VVSDRWNDTT WVYQHYTQGI
PKKLCDQMFD YHLNLPNILA AYPLDKRAWL YNQIKGYATI FLNIDLATSR ARVEERVTAT
SGEKDAFESK PDEFFENLIQ NFRTQFSQRT LLEAGPLFTV DATRDLDSVK QSVVNIVQYI
TD
//
