ID A0A0K2RIL7_9MICC Unreviewed; 641 AA.
AC A0A0K2RIL7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Subtilisin-like protease {ECO:0000313|EMBL:BAS14644.1};
GN ORFNames=AHiyo8_29470 {ECO:0000313|EMBL:BAS14644.1};
OS Arthrobacter sp. Hiyo8.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=1588023 {ECO:0000313|EMBL:BAS14644.1, ECO:0000313|Proteomes:UP000060353};
RN [1] {ECO:0000313|Proteomes:UP000060353}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hiyo8 {ECO:0000313|Proteomes:UP000060353};
RA Hiraoka S., Machiyama A., Iwasaki W.;
RT "Microbial genome analysis of tsunami-affected soil.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; AP014719; BAS14644.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0K2RIL7; -.
DR STRING; 1588023.AHiyo8_29470; -.
DR KEGG; arh:AHiyo8_29470; -.
DR PATRIC; fig|1588023.3.peg.3073; -.
DR Proteomes; UP000060353; Chromosome.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF468; SUBTILISIN-LIKE PROTEASE SBT3.18; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF54897; Protease propeptides/inhibitors; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..38
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 39..641
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005482893"
FT DOMAIN 68..163
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 195..442
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 478..550
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT REGION 573..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..641
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 204
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 305
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 455
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 641 AA; 65881 MW; 6710ED11BB4610E1 CRC64;
MNSQGKSFIG SGGLRKAAAL AVGLPVLLSS VALTPAQAAP ASGSTVLGST AAGVARNVDP
KSYQDGRYVV VLAEKPAATY DGGTPGYVPT KPQAGKKLDV GKAEVKQYQA HLQQKQQDVA
KQQSVTINRD YTTAINGFSA TLSANQAVNL AKNPDVLLVA PDTQSAPDYS TTDFLNLSGP
NGAWNTQFGG QDQAGKGTVV GVIDTGYTPT SKFFAGDPVQ PLVGDPQVGI PYRTSDGKIA
MLKANGDTFV GECQKGTDTG AAFDGTACNS KVLAAHYFAD AFLQTVPPAQ RAPQEQISPI
DVVSHGTHTA STAAGNPGVE TFVDGRSFGK TSGVAPAAKL SIYKVCWEDT DPNTGGCYSS
AAIAAIDQAI ADGVDVLNYS ISGATDTTTD PVSLAFLSAA SAGIFVAASA GNSGPQASTV
NHGAPWMTTV AATSFSQELQ GTVEFSDGTK FRGASIMNHQ VSGAGVVLSA NAASGAGNAA
LCAPGSLDPA KIAGKVVVCD RGVVDRVAKS AEVLRGGGVG MILVNLTSSS LDTDKHAVPT
VHVNPPASQA IKDKVGANRH LLFPWLTTTP LGFRSRPSRR SPDSPPAARS SPPIRISSSR
TSRLPALRCS RVFRRSAAKV MSTDSCPVPP WRPRTLQVSE P
//
