ID A0A0K2YDD5_9NOCA Unreviewed; 469 AA.
AC A0A0K2YDD5;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=diacylglycerol O-acyltransferase {ECO:0000256|ARBA:ARBA00013244};
DE EC=2.3.1.20 {ECO:0000256|ARBA:ARBA00013244};
GN ORFNames=RHCRD62_120074 {ECO:0000313|EMBL:CRK50553.1};
OS Rhodococcus sp. RD6.2.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=260936 {ECO:0000313|EMBL:CRK50553.1, ECO:0000313|Proteomes:UP000044872};
RN [1] {ECO:0000313|EMBL:CRK50553.1, ECO:0000313|Proteomes:UP000044872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RD6.2 {ECO:0000313|EMBL:CRK50553.1,
RC ECO:0000313|Proteomes:UP000044872};
RA Wang D.B., Wang M.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycerol + an acyl-CoA = a triacyl-sn-glycerol
CC + CoA; Xref=Rhea:RHEA:10868, ChEBI:CHEBI:17815, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:58342, ChEBI:CHEBI:64615; EC=2.3.1.20;
CC Evidence={ECO:0000256|ARBA:ARBA00001039};
CC -!- PATHWAY: Glycerolipid metabolism; triacylglycerol biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004771}.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the long-chain O-acyltransferase family.
CC {ECO:0000256|ARBA:ARBA00009587}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CVQP01000004; CRK50553.1; -; Genomic_DNA.
DR RefSeq; WP_050063901.1; NZ_CVQP01000004.1.
DR AlphaFoldDB; A0A0K2YDD5; -.
DR STRING; 260936.RHCRD62_120074; -.
DR UniPathway; UPA00282; -.
DR Proteomes; UP000044872; Unassembled WGS sequence.
DR GO; GO:0004144; F:diacylglycerol O-acyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0019432; P:triglyceride biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR045034; O-acyltransferase_WSD1-like.
DR InterPro; IPR009721; O-acyltransferase_WSD1_C.
DR InterPro; IPR004255; O-acyltransferase_WSD1_N.
DR PANTHER; PTHR31650:SF1; DIACYGLYCEROL O-ACYLTRANSFERASE TGS4-RELATED; 1.
DR PANTHER; PTHR31650; O-ACYLTRANSFERASE (WSD1-LIKE) FAMILY PROTEIN; 1.
DR Pfam; PF06974; WS_DGAT_C; 1.
DR Pfam; PF03007; WS_DGAT_cat; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Glycerol metabolism {ECO:0000256|ARBA:ARBA00022798};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000044872};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 4..267
FT /note="O-acyltransferase WSD1-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03007"
FT DOMAIN 309..461
FT /note="O-acyltransferase WSD1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF06974"
SQ SEQUENCE 469 AA; 51384 MW; 334951722A7FA090 CRC64;
MQQLSAQDAW FLYTDSPRFR QAYVSAYAFA PTDGEGRLPG REETAQWIEQ RAYLPELRRR
LVRTPFDLAH PYWVEDPDFD VARHLRFHDA MTWDRLREFL AGLASALMDD TRPMWELHVV
DRVEEMPGVR GPVAVVAVKM HHCAADGIGS GRVTTALFGS EVGCLDAMST RRGRVPTRPE
LVARAALGVP RTVGGLVAAQ RSAKEKRTAQ LSLRETATYP LPPQRRTPTS LDGPVGPGRV
YEAAVFSLAE MQEVKARIGE VTINDLVLTV VGGALQAYLA EQGETPDGSL AASVPMTVRA
TRPKPGSNNQ FVMTVVDLRT TETDPVTRAR GVRESVLGER SRMSVPAEAA VLDTDFVLPG
WMFRVARELE RRRGGPPTGD PANGRLFNTF VTSVPRRSTP LRLVDATAVM AFGTSTLDGT
GTSHSVGSVG DALVLNITAD PALLKDSRRY AELIRKSYTE LRDAAFSTV
//
