ID A0A0K3AUM4_CAEEL Unreviewed; 667 AA.
AC A0A0K3AUM4;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=F-box domain-containing protein {ECO:0000313|EMBL:CTQ86500.1};
GN Name=lin-23 {ECO:0000313|EMBL:CTQ86500.1,
GN ECO:0000313|WormBase:K10B2.1b};
GN ORFNames=CELE_K10B2.1 {ECO:0000313|EMBL:CTQ86500.1}, K10B2.1
GN {ECO:0000313|WormBase:K10B2.1b};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CTQ86500.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CTQ86500.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CTQ86500.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; BX284602; CTQ86500.1; -; Genomic_DNA.
DR RefSeq; NP_001300561.1; NM_001313632.1.
DR AlphaFoldDB; A0A0K3AUM4; -.
DR SMR; A0A0K3AUM4; -.
DR EnsemblMetazoa; K10B2.1b.1; K10B2.1b.1; WBGene00003009.
DR GeneID; 174058; -.
DR KEGG; cel:CELE_K10B2.1; -.
DR AGR; WB:WBGene00003009; -.
DR WormBase; K10B2.1b; CE50404; WBGene00003009; lin-23.
DR OMA; PTHTACY; -.
DR OrthoDB; 337075at2759; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00003009; Expressed in pharyngeal muscle cell (C elegans) and 4 other cell types or tissues.
DR ExpressionAtlas; A0A0K3AUM4; baseline and differential.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 6.10.250.1840; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR021977; Beta-TrCP_D.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR14604:SF4; F-BOX DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR14604; WD40 REPEAT PF20; 1.
DR Pfam; PF12125; Beta-TrCP_D; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM01028; Beta-TrCP_D; 1.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50181; FBOX; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 4.
DR PROSITE; PS50082; WD_REPEATS_2; 7.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:A0A0K3AUM4,
KW ECO:0007829|PeptideAtlas:A0A0K3AUM4};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 81..127
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT REPEAT 218..248
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 258..297
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 298..337
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 341..380
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 381..420
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 421..453
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 470..500
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 574..667
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 667 AA; 76192 MW; FD64A4C36A03AD88 CRC64;
MSSPHRASTT QQLADLSLTE GEHDEGKPLS IDYLQGHEGL IEEVLKWSEH EQLDFMDKIV
HRLSHYQLGK VDNFIRPMLQ RDFISNLPAH LVELILFNVN SDSLKSCEEV STSWRCALAR
GQHWKKLIEK NVRSDSLWWG LSEKRQWDKF LNISRDMSVR RICEKFNYDV NIKRDKLDQL
ILMHVFYSKL YPKIIRDIHN IDNNWKRGNY KMTRINCQSE NSKGVYCLQY DDDKIVSGLR
DNTIKIWDRK DYSCSRILSG HTGSVLCLQY DNRVIISGSS DATVRVWDVE TGECIKTLIH
HCEAVLHLRF ANGIMVTCSK DRSIAVWDMV SPRDITIRRV LVGHRAAVNV VDFDDRYIVS
ASGDRTIKVW SMDTLEFVRT LAGHRRGIAC LQYRGRLVVS GSSDNTIRLW DIHSGVCLRV
LEGHEELVRC IRFDEKRIVS GAYDGKIKVW DLQAALDPRA LSSEICLCSL VQHTGRVFRL
QFDDFQIVSS SHDDTILIWD FLDAPPSGLP SSTNRATLPE LPNQAAVARA QMLFEMAARR
EIERRDREVV EEPALRPRAN AARRHNADIA AAAAAAEAAR GAGDNDESSS EEDLDRVDQV
NNPNVAGPAP PQPHNQNHRR RQPRPELPVR LMFQQEMAAF DNMRRQQNNM DHLGGGDVDE
EMPDGGP
//
