ID A0A0K3C7Y7_RHOTO Unreviewed; 247 AA.
AC A0A0K3C7Y7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=NAD(P)H-hydrate epimerase {ECO:0000256|ARBA:ARBA00012228};
DE EC=5.1.99.6 {ECO:0000256|ARBA:ARBA00012228};
DE Flags: Fragment;
GN Name=FGENESH: predicted gene_1.471 {ECO:0000313|EMBL:CTR04610.1};
GN ORFNames=BN2166_0004710 {ECO:0000313|EMBL:CTR04610.1};
OS Rhodotorula toruloides (Yeast) (Rhodosporidium toruloides).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Sporidiobolales; Sporidiobolaceae; Rhodotorula.
OX NCBI_TaxID=5286 {ECO:0000313|EMBL:CTR04610.1, ECO:0000313|Proteomes:UP000199069};
RN [1] {ECO:0000313|EMBL:CTR04610.1, ECO:0000313|Proteomes:UP000199069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Single colony {ECO:0000313|EMBL:CTR04610.1};
RA Cajimat M.N.B., Milazzo M.L., Fulhorst C.F.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(6R)-NADHX = (6S)-NADHX; Xref=Rhea:RHEA:32215,
CC ChEBI:CHEBI:64074, ChEBI:CHEBI:64075; EC=5.1.99.6;
CC Evidence={ECO:0000256|ARBA:ARBA00000013};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(6R)-NADPHX = (6S)-NADPHX; Xref=Rhea:RHEA:32227,
CC ChEBI:CHEBI:64076, ChEBI:CHEBI:64077; EC=5.1.99.6;
CC Evidence={ECO:0000256|ARBA:ARBA00000909};
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DR EMBL; CWKI01000001; CTR04610.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0K3C7Y7; -.
DR STRING; 5286.A0A0K3C7Y7; -.
DR OMA; RHLFHYG; -.
DR Proteomes; UP000199069; Unassembled WGS sequence.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.10260; YjeF N-terminal domain; 1.
DR HAMAP; MF_01966; NADHX_epimerase; 1.
DR InterPro; IPR004443; YjeF_N_dom.
DR InterPro; IPR036652; YjeF_N_dom_sf.
DR InterPro; IPR032976; YJEFN_prot_NAXE-like.
DR NCBIfam; TIGR00197; yjeF_nterm; 1.
DR PANTHER; PTHR13232; NAD(P)H-HYDRATE EPIMERASE; 1.
DR PANTHER; PTHR13232:SF10; NAD(P)H-HYDRATE EPIMERASE; 1.
DR Pfam; PF03853; YjeF_N; 1.
DR SUPFAM; SSF64153; YjeF N-terminal domain-like; 1.
DR PROSITE; PS51385; YJEF_N; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000199069}.
FT DOMAIN 18..247
FT /note="YjeF N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51385"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CTR04610.1"
FT NON_TER 247
FT /evidence="ECO:0000313|EMBL:CTR04610.1"
SQ SEQUENCE 247 AA; 26516 MW; 0EC2E895B420841D CRC64;
AFRAPAPRQP KYISAKEAQD IDAWLMGGDD KGAFSLDQLM ELAGLSVAQA VARLYPLGPK
LPPDANGVKQ KRTNERVLVC CGPGNQGGDG LVAARHLYHF GYAPSVFYPK ESSGEIFSRL
KKQCENLDLP LIAPPAHSSS SFPMAADAQD VAFRRAMENT DVVLDCVFGF SFQPPARAPF
ITVLDEFKKT TKPILSVDIP SGWDVVDGNP GDGFTPDSLL SLTAPKLGVK SFVESGGKHL
LGGRFIP
//
