ID A0A0K6H8W2_9NEIS Unreviewed; 849 AA.
AC A0A0K6H8W2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=Ga0061063_0092 {ECO:0000313|EMBL:CUA87173.1};
OS Gulbenkiania indica.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
OC Chromobacteriaceae; Gulbenkiania.
OX NCBI_TaxID=375574 {ECO:0000313|EMBL:CUA87173.1, ECO:0000313|Proteomes:UP000243535};
RN [1] {ECO:0000313|Proteomes:UP000243535}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17901 {ECO:0000313|Proteomes:UP000243535};
RA Varghese N.;
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CYHA01000011; CUA87173.1; -; Genomic_DNA.
DR RefSeq; WP_055434539.1; NZ_LION01000011.1.
DR AlphaFoldDB; A0A0K6H8W2; -.
DR STRING; 375574.GCA_001418035_02675; -.
DR OrthoDB; 8579121at2; -.
DR Proteomes; UP000243535; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.350; CHASE domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR006189; CHASE_dom.
DR InterPro; IPR042240; CHASE_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF03924; CHASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000243535};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 347..391
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 420..470
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 555..606
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 624..845
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 849 AA; 93327 MW; 35C62FB07AEFA4B5 CRC64;
MPALRPRTWL VLWFMFTAGA LGLQAMLAHR DADRQALAQR TQAAQTRLAL LESRLYSQLN
AVGFLANSLG GADPDTLMRV LARLPGLQTP AEPLLTGAGL VSRVPNAGRI AFEDSLGTSI
RAPHEGRLYP SPSLPVYFPV RFYAPDTAEG LPQGFDTGSL PGWNLALESA RENHQPYLLP
PSSLDAQNGA LHMVASLPDR DDIVLVRLSR RRLLDLTSPS GPTDGLRLVV WQQGRNPAPF
LDTLPQAPLP TARPLLSAKR VFGGLPVMVT VFSLGDTLPV SANLPATLLP TFLFALLVLG
GGWLLVGWQR RLSAEVVRQE QALRDSTEQL QAQRAEHSLS QRALTESEAR QRAILQASSD
AILLIDHDGR ITHANPAAAR LIGQSAVSVE GLPIGVLLSE LYRTDGRAGF RTLAMRHAGY
PFEAHLVRND NSRLPVEVTL SQVILPNDRF YVAVCRDISV RKEQEAALIR LKNSLAEQVE
VQRRQLSALL EASPLAMAYV VNRDFKQVNR AFLEMFRLAE DQTNNLSTRI LYDSDTHWER
AGRLFFDHVN DGRVIHSEQR LVTGDGTPIW CRMYGKVVNP SMPGLGSVWV YQDISAQRAA
EEALRDAKNL AEETSRAKTE FLANMSHELR TPMHAVLGFA EMGATRVEEA SREKLGQYFE
RIHTSGRRLM GLLNDLLDLA KMEAGRMEYH FEALDVAGLL AEACEEMASL AERSGLRFEV
TAPEGLSGQW DSQRIRQVVV NLLSNAIRFS PPQGVIELTA RRLPALPDER IEISVTDHGP
GIPPAELESI FDKFIQSSST KTGAGGTGLG LAICREIVTA HQGQIHADNA PHGGARFAFI
LPVHPVSHR
//
