ID A0A0K6IVD1_9PROT Unreviewed; 292 AA.
AC A0A0K6IVD1;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Ribose-phosphate pyrophosphokinase {ECO:0000313|EMBL:CUB07048.1};
GN ORFNames=Ga0061068_104177 {ECO:0000313|EMBL:CUB07048.1};
OS Tepidiphilus thermophilus.
OC Bacteria; Pseudomonadota; Hydrogenophilia; Hydrogenophilales;
OC Hydrogenophilaceae; Tepidiphilus.
OX NCBI_TaxID=876478 {ECO:0000313|EMBL:CUB07048.1, ECO:0000313|Proteomes:UP000182108};
RN [1] {ECO:0000313|Proteomes:UP000182108}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 19170 {ECO:0000313|Proteomes:UP000182108};
RA Babu N.S., Beckwith C.J., Beseler K.G., Brison A., Carone J.V.,
RA Caskin T.P., Diamond M., Durham M.E., Foxe J.M., Go M., Henderson B.A.,
RA Jones I.B., McGettigan J.A., Micheletti S.J., Nasrallah M.E., Ortiz D.,
RA Piller C.R., Privatt S.R., Schneider S.L., Sharp S., Smith T.C.,
RA Stanton J.D., Ullery H.E., Wilson R.J., Serrano M.G., Buck G., Lee V.,
RA Wang Y., Carvalho R., Voegtly L., Shi R., Duckworth R., Johnson A.,
RA Loviza R., Walstead R., Shah Z., Kiflezghi M., Wade K., Ball S.L.,
RA Bradley K.W., Asai D.J., Bowman C.A., Russell D.A., Pope W.H.,
RA Jacobs-Sera D., Hendrix R.W., Hatfull G.F.;
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ribose-phosphate pyrophosphokinase family.
CC {ECO:0000256|RuleBase:RU004324}.
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DR EMBL; CYHH01000004; CUB07048.1; -; Genomic_DNA.
DR RefSeq; WP_055423363.1; NZ_LIPU01000004.1.
DR AlphaFoldDB; A0A0K6IVD1; -.
DR OrthoDB; 324294at2; -.
DR Proteomes; UP000182108; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
DR GO; GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 2.
DR InterPro; IPR029099; Pribosyltran_N.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR005946; Rib-P_diPkinase.
DR NCBIfam; TIGR01251; ribP_PPkin; 1.
DR PANTHER; PTHR10210; RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER; 1.
DR PANTHER; PTHR10210:SF119; RIBOSE-PHOSPHATE PYROPHOSPHOKINASE; 1.
DR Pfam; PF00156; Pribosyltran; 1.
DR Pfam; PF13793; Pribosyltran_N; 1.
DR SMART; SM01400; Pribosyltran_N; 1.
DR SUPFAM; SSF53271; PRTase-like; 2.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:CUB07048.1};
KW Nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022727,
KW ECO:0000256|RuleBase:RU004324};
KW Reference proteome {ECO:0000313|Proteomes:UP000182108};
KW Transferase {ECO:0000313|EMBL:CUB07048.1}.
FT DOMAIN 8..106
FT /note="Ribose-phosphate pyrophosphokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13793"
FT DOMAIN 155..245
FT /note="Phosphoribosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00156"
SQ SEQUENCE 292 AA; 31168 MW; 6189884F956ABAB7 CRC64;
MLLFFPEEEG FARRLAAATG LEAAPIERHR FPDEEIKLRL PERLPEKVVL LRGLDRPNEK
LVELLLASAG LHEAGVRRIV LVAPYFPYLR QDKAFAPGEV ASAFVVGRFV ASCVEALVTV
DPHLHRIARL DEAVPVTPAL ALCAAPLLGE LAARERGRPL LVGPDEESRA WVEAAAHASG
LEYAVGRKER RGDRDVAVTL PEGLNVRGRA AVVLDDVAST GRTLAQAVRA LRSAGAATVD
VAVTHALFVE DALETVRAAG AGAIWSTDTI AHPTNAVSVA PLIAQALAAL LR
//
