ID   A0A0K8J5L7_9FIRM        Unreviewed;       468 AA.
AC   A0A0K8J5L7;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=HTH gntR-type domain-containing protein {ECO:0000259|PROSITE:PS50949};
GN   ORFNames=SD1D_1214 {ECO:0000313|EMBL:CUH92760.1};
OS   Herbinix luporum.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Herbinix.
OX   NCBI_TaxID=1679721 {ECO:0000313|EMBL:CUH92760.1, ECO:0000313|Proteomes:UP000196053};
RN   [1] {ECO:0000313|Proteomes:UP000196053}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SD1D {ECO:0000313|Proteomes:UP000196053};
RA   Wibberg D.;
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC       pyridoxal-phosphate-dependent aminotransferase family.
CC       {ECO:0000256|ARBA:ARBA00005384}.
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DR   EMBL; LN879430; CUH92760.1; -; Genomic_DNA.
DR   RefSeq; WP_058258100.1; NZ_LN879430.1.
DR   AlphaFoldDB; A0A0K8J5L7; -.
DR   KEGG; hsd:SD1D_1214; -.
DR   OrthoDB; 9808770at2; -.
DR   Proteomes; UP000196053; Chromosome i.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00609; AAT_like; 1.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR   PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   Pfam; PF00392; GntR; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000196053};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          12..80
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50949"
SQ   SEQUENCE   468 AA;  53969 MW;  2E731A93966F4BA8 CRC64;
     MLTYSFDNRG KDTLYEYLYK QIKNDIYSNK LRPNEKLPSK RALAKHLNIS TITVENAYSQ
     LVAEGYIYSI PKSGYYVSDI SANILKSDNH IGDNLTDDKT EKNRSDNYFI DFVNNSTDPE
     NFPFTIWTKL MRETMSEKRS DLMIKSPSIG VYQLRRAIAD YLYQFRGIET KPEQILVGAG
     TEYLYGLIIQ LLGHNKKYAV EDPGYQKVSR IYGANKVDCV HIPLDDNGIN VEALEESKAN
     VLHITPSHHF PTGLVTPISR RYELLSWASK SKDRYIIEDD YDSEFRLLGK PIPALQSIDA
     AEKVIYINTF SKSLTSTIRI SYMVLPKSLM ERYNKELSFY SCTVSNFEQY TLAKFIEQGY
     LEKHINRMRN HYRNIRDDIL ENIKKALGKK KGKIMEEDAG LHFLLQISTD LTDKELISRA
     AKNGINISCL SQYYYDQANA IKNTLIINYS GVNPDNIEEG IKRLFQCF
//