ID A0A0K8JAV1_9FIRM Unreviewed; 319 AA.
AC A0A0K8JAV1;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha {ECO:0000313|EMBL:CUH94762.1};
DE EC=1.1.1.- {ECO:0000313|EMBL:CUH94762.1};
GN Name=acoA {ECO:0000313|EMBL:CUH94762.1};
GN ORFNames=P22_0828 {ECO:0000313|EMBL:CUH94762.1};
OS Propionispora sp. 2/2-37.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC Propionispora.
OX NCBI_TaxID=1677858 {ECO:0000313|EMBL:CUH94762.1, ECO:0000313|Proteomes:UP000041641};
RN [1] {ECO:0000313|EMBL:CUH94762.1, ECO:0000313|Proteomes:UP000041641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2/2 {ECO:0000313|EMBL:CUH94762.1};
RA Jackson K.R., Lunt B.L., Fisher J.N.B., Gardner A.V., Bailey M.E.,
RA Deus L.M., Earl A.S., Gibby P.D., Hartmann K.A., Liu J.E., Manci A.M.,
RA Nielsen D.A., Solomon M.B., Breakwell D.P., Burnett S.H., Grose J.H.;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR EMBL; CYSP01000003; CUH94762.1; -; Genomic_DNA.
DR RefSeq; WP_054258954.1; NZ_CYSP01000003.1.
DR AlphaFoldDB; A0A0K8JAV1; -.
DR STRING; 1677858.P22_0828; -.
DR OrthoDB; 9766715at2; -.
DR Proteomes; UP000041641; Unassembled WGS sequence.
DR GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR029061; THDP-binding.
DR PANTHER; PTHR11516:SF60; PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA; 1.
DR PANTHER; PTHR11516; PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR; 1.
DR Pfam; PF00676; E1_dh; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CUH94762.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000041641}.
FT DOMAIN 14..309
FT /note="Dehydrogenase E1 component"
FT /evidence="ECO:0000259|Pfam:PF00676"
SQ SEQUENCE 319 AA; 35067 MW; C7FF6D53C6DD2838 CRC64;
MKVRKEELLK WYRKMLHTRF FESQVDAFFA KGMIHGTTHL SIGQEAFAIG STAALREDDL
ITSTHRGHGE CIGKDADVNL MMAELMGKSN GYCKGKGGSM HIADLEKGNL GANGVVGGGF
AIAVGAALTQ QMKKTGKVVL CYFGDGASNE GSFHESLNMA AIWKLPVVFM CTNNKYGMSM
STQRSMKIEH VAERAVAYGM PGVTVDGNDV LKVYEATLEA VERARRGEGP SIVEGLTYRW
LGHSKSDANR YRTKEEIESW KEKCPIKAFE KYLVDNKICT QAECEVMTAA AKEDIARAVE
FAQQGSYPGI ETLEEDVYA
//
