ID A0A0K8MCX8_9PROT Unreviewed; 635 AA.
AC A0A0K8MCX8;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Adenylate cyclase 1 {ECO:0000313|EMBL:GAO98058.1};
GN Name=cyaA_1 {ECO:0000313|EMBL:GAO98058.1};
GN ORFNames=Cva_00701 {ECO:0000313|EMBL:GAO98058.1};
OS Caedimonas varicaedens.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Holosporales;
OC Caedimonadaceae; Caedimonas.
OX NCBI_TaxID=1629334 {ECO:0000313|EMBL:GAO98058.1, ECO:0000313|Proteomes:UP000036771};
RN [1] {ECO:0000313|EMBL:GAO98058.1, ECO:0000313|Proteomes:UP000036771}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Suzuki H., Dapper A.L., Gibson A.K., Jackson C., Lee H., Pejaver V.R.,
RA Doak T., Lynch M.;
RT "Caedibacter varicaedens, whole genome shotgun sequence.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the adenylyl cyclase class-3 family.
CC {ECO:0000256|ARBA:ARBA00005381}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAO98058.1}.
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DR EMBL; BBVC01000023; GAO98058.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0K8MCX8; -.
DR STRING; 1629334.Cva_00701; -.
DR OrthoDB; 9789782at2; -.
DR Proteomes; UP000036771; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR CDD; cd12913; PDC1_MCP_like; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000036771};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 358..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 377..430
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 457..589
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 635 AA; 73091 MW; B14AF8726B5BB2A4 CRC64;
MIYSRIKAKK IQAVILFWTL LLLFFSAITT LSYTYINNKK SILRQSEDFI KETSKGFVKD
TMDYFLEVEK LAKILAPLFK EEDFTNNVNH PKIFSLLETV NLYPQITSLY FGYDTGYFLA
VFMTQKGAQF RTSDNLLPSS IISALRIIKE KGDRLIEEWY YFNNEEEQIR SEIVEATTYD
PRDRSWYKAA SKSLNTEWSD VYVFIGSIKE PGITVSYPIL LNKNATLKGV IAVDISIKNL
SKFLASNKFT PNLKSYIIND KQEIIATSDP INNIVFGNND FKVLSINEMG DCILKYTDQL
YREKNKSENI IKFEYKNVDY YAVYTDFPST FMKNWKIVLI YPLDDFIKEI KENNKESLLI
SLLILIFSSF LMVLVARRIS RPIIQLSKEA EKIREFKLFD NISVQTSIKE IQTLAHSMEN
MKTSFGSFAK YVPHTLVSKL VRKNQSIQIG GKIKEITLLF TDITDFTSVS EPISADKVAT
YLSDYFDELT KIIMHTEGTI DKYIGDSIMA FWGAPIPDKN NSFNACLAAL LCQKKLIEIN
ALWHHDHKPV FKTRFGIHTG EAVVGNIGSS ERMNYTAIGD NVNLCSRLEG LNKIYGTQII
ISETVYDRVK NKFLTRPLDW VEVKGKTQPI KIFEL
//
