ID A0A0K8NTU4_IDESA Unreviewed; 1038 AA.
AC A0A0K8NTU4;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:GAP33807.1};
GN ORFNames=ISF6_1062 {ECO:0000313|EMBL:GAP33807.1};
OS Ideonella sakaiensis (strain NBRC 110686 / TISTR 2288 / 201-F6).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Piscinibacter.
OX NCBI_TaxID=1547922 {ECO:0000313|EMBL:GAP33807.1, ECO:0000313|Proteomes:UP000037660};
RN [1] {ECO:0000313|Proteomes:UP000037660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 110686 / TISTR 2288 / 201-F6
RC {ECO:0000313|Proteomes:UP000037660};
RA Yoshida S., Hiraga K., Takehana T., Taniguchi I., Yamaji H., Maeda Y.,
RA Toyohara K., Miyamoto K., Kimura Y., Oda K.;
RT "Discovery of a poly(ethylene terephthalate assimilation.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GAP33807.1, ECO:0000313|Proteomes:UP000037660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 110686 / TISTR 2288 / 201-F6
RC {ECO:0000313|Proteomes:UP000037660};
RX PubMed=26965627; DOI=10.1126/science.aad6359;
RA Yoshida S., Hiraga K., Takehana T., Taniguchi I., Yamaji H., Maeda Y.,
RA Toyohara K., Miyamoto K., Kimura Y., Oda K.;
RT "A bacterium that degrades and assimilates poly(ethylene terephthalate).";
RL Science 351:1196-1199(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAP33807.1}.
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DR EMBL; BBYR01000002; GAP33807.1; -; Genomic_DNA.
DR RefSeq; WP_054017964.1; NZ_BBYR01000002.1.
DR AlphaFoldDB; A0A0K8NTU4; -.
DR STRING; 1547922.ISF6_1062; -.
DR OrthoDB; 8864477at2; -.
DR Proteomes; UP000037660; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR007890; CHASE2.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF05226; CHASE2; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM01080; CHASE2; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000037660};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 400..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 631..775
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 784..1038
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 1038 AA; 111085 MW; 84BF9EA12C1D6229 CRC64;
MGRAARPTGR PTAARALVFA LIGLLAFALT AFAWSQRSKV PLLSNLDGLV LDWQLHRRGP
QAPASPVPVR MLMHDERSAM ELGSGIPRTT LADTIDRLAT EGAAWIAVDI LLTEATEPAV
DQRLADAIRR AGNVVIPYAL PDQSLSRGQA AAPAASAASA ASVARAAPIA ATGPTGTAAA
AGVPEPILDS AFHRYRHEER AALMALKPGM MLAPIGPLLE AARGLGHVSV QQRLDGTLRH
DLPAVKFDDE IYPSLAATLT ALATGVAPAE MEVSLGESLT IGTRRVPLDL TSQLWVNYLG
PRGTIPLYSL ADHVAGRLPA DRFRGAIVLI GSDALGSGDR YRSPFDVGLP GTERLATVID
NLMARHWLER PAWAATAESA AMLVLPVGVA LGLAVAPPAW VLGAAALLGL ACFGVSQWLF
EQRLQMVSPL FPVLALLLAA GLAMAWRSVL YERERRAAER RLRASEQRFA LAARGANDGL
WDWDLEAGST YLSPRARQMM GLPEAVPDGG ADAGDPIAAW LEGLAPAQAA RLREEIAAHL
DGRTQQLHLE LQHRRAGEDR WTLVRGVAVR EHGRAVRMAG SLTDITEPKR LEQQVVFDAI
HDRLTGLANR ELFADRLGQW LRPQAAGQPA GPLGLVLLDI DGFRQINEVH GHVSGNQVLV
EVAARLRALS DARPGGALVA RVGADQFAVA APGPLDALVA LAHDAQAALA APLAALAPAG
EAAHPADAGG LSVTAAVAHT EHGLDGVDEL MNGADLAMSQ AKRAGHRGRL RSFDPAEQAQ
QTTRRWLNEH IDRALAAGDQ FQLHYQPFVR LSDRALIGFE ALIRWKHPER GMVMPGDFIP
HAEQTGQINA IGQWTLFEAA RQLVAWDAIG FTGEVAVNLS GRQFTETDLE ADARRVLELL
GPVAPKRYKL EVTESMAMEN PQRTAKVLNR LADMGFKISI DDFGTGYSSL AYLHRFPFDT
LKIDRSFVIR LGAGREAQEI VRTIVGLGAA LDKQVLAEGV EEEAQAQTLQ ALGVHTGQGW
LFAKALPADA ATAHIRRG
//
