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Database: UniProt
Entry: A0A0K8P5E7_IDESA
LinkDB: A0A0K8P5E7_IDESA
Original site: A0A0K8P5E7_IDESA 
ID   A0A0K8P5E7_IDESA        Unreviewed;       512 AA.
AC   A0A0K8P5E7;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   16-JAN-2019, entry version 23.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=ISF6_3782 {ECO:0000313|EMBL:GAP37837.1};
OS   Ideonella sakaiensis (strain 201-F6).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Ideonella.
OX   NCBI_TaxID=1547922 {ECO:0000313|EMBL:GAP37837.1, ECO:0000313|Proteomes:UP000037660};
RN   [1] {ECO:0000313|Proteomes:UP000037660}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=201-F6 {ECO:0000313|Proteomes:UP000037660};
RA   Yoshida S., Hiraga K., Takehana T., Taniguchi I., Yamaji H., Maeda Y.,
RA   Toyohara K., Miyamoto K., Kimura Y., Oda K.;
RT   "Discovery of a poly(ethylene terephthalate assimilation.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:GAP37837.1, ECO:0000313|Proteomes:UP000037660}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=201-F6 {ECO:0000313|EMBL:GAP37837.1,
RC   ECO:0000313|Proteomes:UP000037660};
RX   PubMed=26965627; DOI=10.1126/science.aad6359;
RA   Yoshida S., Hiraga K., Takehana T., Taniguchi I., Yamaji H., Maeda Y.,
RA   Toyohara K., Miyamoto K., Kimura Y., Oda K.;
RT   "A bacterium that degrades and assimilates poly(ethylene
RT   terephthalate).";
RL   Science 351:1196-1199(2016).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:GAP37837.1}.
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DR   EMBL; BBYR01000059; GAP37837.1; -; Genomic_DNA.
DR   EnsemblBacteria; GAP37837; GAP37837; ISF6_3782.
DR   Proteomes; UP000037660; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000037660};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037660}.
FT   DOMAIN      209    343       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      420    489       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     217    224       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   512 AA;  56466 MW;  5256E51680AE6287 CRC64;
     MDNRPRPAPA GVESRPLPEN FSTTMSADLW QRGCERLAAE LPEIQYNTWI RPLAPAEITE
     VGGKDDAAGA TLVATLQVPN RFKLDWIRSQ YGARIEHVLS ELAGRAVRLE VGVVPGAGAD
     PRRLATRHLV ATTDATTRVP LPPGAVAGAG LPGAAAPRAG DAGSAARARP PEPTHRLNTQ
     WTFENLVPGR ANQMARTAAL HVAGAPGQMY NPLFIYGGVG LGKTHLIHAV GNALLADRPD
     ARILYLHAEQ FISDVVKNYQ RKTFDELKAK YHSLDLLLID DVQFFAGKER TQEEFFNAFE
     ALLAKRAHII MTSDTYPKGL VDIDERLTSR FDAGLTVAIE PPELEMRVAI LMRKAEAEAT
     VMPEDVAFFV AKNVRANVRE LEGALRKVLA YARFSHKDIN IALAREALKD LLSIQNRQIG
     VENIQKTVAD FYKIKVADMY SKKRPASIAR PRQIAMYLAK EMTQKSLPEI GELFGGRDHT
     TVLHAVRKIG GERQKNTELN QQLHVLEQTL KG
//
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