ID A0A0K9NMV9_ZOSMR Unreviewed; 1303 AA.
AC A0A0K9NMV9;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Fanconi anemia group M protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ZOSMA_80G00400 {ECO:0000313|EMBL:KMZ57948.1};
OS Zostera marina (Eelgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Zosteraceae; Zostera.
OX NCBI_TaxID=29655 {ECO:0000313|EMBL:KMZ57948.1, ECO:0000313|Proteomes:UP000036987};
RN [1] {ECO:0000313|Proteomes:UP000036987}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Finnish {ECO:0000313|Proteomes:UP000036987};
RX PubMed=26814964; DOI=10.1038/nature16548;
RA Olsen J.L., Rouze P., Verhelst B., Lin Y.-C., Bayer T., Collen J.,
RA Dattolo E., De Paoli E., Dittami S., Maumus F., Michel G., Kersting A.,
RA Lauritano C., Lohaus R., Toepel M., Tonon T., Vanneste K., Amirebrahimi M.,
RA Brakel J., Bostroem C., Chovatia M., Grimwood J., Jenkins J.W.,
RA Jueterbock A., Mraz A., Stam W.T., Tice H., Bornberg-Bauer E., Green P.J.,
RA Pearson G.A., Procaccini G., Duarte C.M., Schmutz J., Reusch T.B.H.,
RA Van de Peer Y.;
RT "The genome of the seagrass Zostera marina reveals angiosperm adaptation to
RT the sea.";
RL Nature 530:331-335(2016).
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC FANCM sub-subfamily. {ECO:0000256|ARBA:ARBA00009889}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMZ57948.1}.
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DR EMBL; LFYR01001997; KMZ57948.1; -; Genomic_DNA.
DR STRING; 29655.A0A0K9NMV9; -.
DR OrthoDB; 12149at2759; -.
DR Proteomes; UP000036987; Unassembled WGS sequence.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000400; F:four-way junction DNA binding; IBA:GO_Central.
DR GO; GO:0009378; F:four-way junction helicase activity; IBA:GO_Central.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0045003; P:double-strand break repair via synthesis-dependent strand annealing; IBA:GO_Central.
DR GO; GO:0036297; P:interstrand cross-link repair; IBA:GO_Central.
DR CDD; cd18033; DEXDc_FANCM; 1.
DR CDD; cd12091; FANCM_ID; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR039686; FANCM/Mph1-like_ID.
DR InterPro; IPR044749; FANCM_DEXDc.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR14025; FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER; 1.
DR PANTHER; PTHR14025:SF20; FANCONI ANEMIA GROUP M PROTEIN; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000036987}.
FT DOMAIN 154..322
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 434..596
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 905..930
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1079..1118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1137..1165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1079..1095
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1303 AA; 146722 MW; 7E271676586BC25E CRC64;
MPSPSSHFVP IPPSIVIDDD DDDFDWDAAI REIDSTCANV ASASGCENAA STIPSGKTER
PSVGSFRQAT LDCFVKKIAK TYDGTSFGRN QVDDHTHHDG IFDDSDIHAQ NGAHLNHLHT
TTTARGQNVA IDLEAAKTWV YPSNVSHRDY QFSITEKALY SNTMVVLPTG LGKTLIAAVV
MYNYFRWFPE GKIVFTAPSR PLVMQQIEAC HKIVGMPQEL TIDMTGNTNP RNRIELWKEK
RVFFVTPQVL EKDIQTGICL TKKLVCLVID EAHRASGNYS YCVVLRELIA ASVDLRILAL
TATPGTRKEN VQNVIDNLCI STLEYRDENN HDVSKYINDR KSELIKVPMD KGANEILSLF
IQIIKQYVIS LNSKGVLPPR DCTVMTPSEW VNIKTIFGNE VSTKFGSAEK AKIMSDIGMM
ISLSYIRQLL LGYGIRLAYV MLEEKLKGPL AKLCHNELIC KTRDLMSKYL SHGAPYPKLS
KLMELLKDHF GNKLLKGQSQ KTQQAVLQKF RSGEYNVIVS TSIGEEGLDI IEVDLVICFD
ANISSLRMTQ RMGRTGRKNS HELNGHLRKQ ATGRAIKKKM FNGGVNSFDF HLSPRMVPHC
CKPKLHIVEF LVGEFIHFGR KTKATPMGRS LLSGILSTEE NDTISKYFHH PNEDDWKPSL
IAFPHFQTFP SRIHRVGHSM KTVHMFINAM EYLQMSPSSK PNVVLPVEAA KKLISEDSDI
RLKGVYDFPE QTSCFEPLSL SNPDAVFENY KLEFASQKAG HQFLFETNFV SVNTLGEVVI
ASFPTLPFID VSDIRSDLSH DHRTKPTYLY EASMFHYNKK TLIPRDALIL SKLSDSRYTD
SEDVFACQPY IYKEKSKEET YPKEEILHQT PLSTQEMLVS KDNLQMSKVS NSILPACESA
SARNHFDSSP KFSSKHGHSD SETNHSFSSS INHDHENCEL LTDHHSINSH IRSNLGNDTF
HGQLNTEEKY DSDYALDDKT NAQVNTNITF NNQVIDGSPG DWLMKLESPK TVQVAPKFKR
LRKYNDTVQK LPFTDFERNA SETNINLHHI AEDGFCQKRR GLDKKMTLVK SFIEEEADVS
ADVDVSEDED DDKDEKGEFN NSFIDDRSNP SEASAHEENS IDMMAFYRRS LLTQSPLETP
SYPISSSHEE ITSTRSEKTD PCLPDEINNS ILISRDEMNH SAKPTSGYST ERITSFELVG
EAIEAQDDWS VIGSKKRKLF HQCPETGLVA KMQPRDLFQS NNSTTSSVPT HTSTDLSCDD
DFFENIDLDA LEAQAIELLK NKPKANELPA CNPVSFPSFD LGL
//
