ID A0A0K9PLA6_ZOSMR Unreviewed; 1418 AA.
AC A0A0K9PLA6;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Pleiotropic drug resistance protein 6 {ECO:0000313|EMBL:KMZ69734.1};
GN ORFNames=ZOSMA_208G00270 {ECO:0000313|EMBL:KMZ69734.1};
OS Zostera marina (Eelgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Zosteraceae; Zostera.
OX NCBI_TaxID=29655 {ECO:0000313|EMBL:KMZ69734.1, ECO:0000313|Proteomes:UP000036987};
RN [1] {ECO:0000313|Proteomes:UP000036987}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Finnish {ECO:0000313|Proteomes:UP000036987};
RX PubMed=26814964; DOI=10.1038/nature16548;
RA Olsen J.L., Rouze P., Verhelst B., Lin Y.-C., Bayer T., Collen J.,
RA Dattolo E., De Paoli E., Dittami S., Maumus F., Michel G., Kersting A.,
RA Lauritano C., Lohaus R., Toepel M., Tonon T., Vanneste K., Amirebrahimi M.,
RA Brakel J., Bostroem C., Chovatia M., Grimwood J., Jenkins J.W.,
RA Jueterbock A., Mraz A., Stam W.T., Tice H., Bornberg-Bauer E., Green P.J.,
RA Pearson G.A., Procaccini G., Duarte C.M., Schmutz J., Reusch T.B.H.,
RA Van de Peer Y.;
RT "The genome of the seagrass Zostera marina reveals angiosperm adaptation to
RT the sea.";
RL Nature 530:331-335(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000256|ARBA:ARBA00006012}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMZ69734.1}.
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DR EMBL; LFYR01000753; KMZ69734.1; -; Genomic_DNA.
DR STRING; 29655.A0A0K9PLA6; -.
DR OMA; FCISNWA; -.
DR OrthoDB; 1384804at2759; -.
DR Proteomes; UP000036987; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013581; PDR_assoc.
DR PANTHER; PTHR48040:SF12; ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48040; PLEIOTROPIC DRUG RESISTANCE PROTEIN 1-LIKE ISOFORM X1; 1.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF08370; PDR_assoc; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000036987};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 504..524
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 544..568
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 588..610
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 616..637
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 649..669
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 731..758
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1165..1183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1195..1218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1239..1263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1275..1297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1304..1325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1388..1410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 135..408
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 816..1068
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1418 AA; 161335 MW; F853D7B28C06B584 CRC64;
MWNAGVDDPV FSRGSSFRED DEEALRWAAL ERLPTFDRVR RGILFRNDSG GCDEVEVSRL
GFEDRLAVIA RVLGDGSDRE NFFTRIRERF DRVHLEFPKI EVRFQNLTVE AFVHLGSRAL
PTIPNFLCNM TEAFLRQLGC FLSERKRLSI LNDISGIIRP SRMTLLLGPP SSGKTTLLMA
LAGRLEGGLQ TSGSVIYNGH KLSEFVPQRT SFYVSQQDCH AAEITVRETL EFSGQCQGVG
YLYDMLMELS RREKRERIKP DEDIDIFLKG LALEGQEVSS IVEYILKILG LDVCANIMVG
NEVVKGISGG QKKRLTTGEL LVGPARVLFM DEISNGLDSS STYEIVKYLR HSTHALDGTT
VISLLQPAPE TFELFDDIIL ICEGQIVYQG ARDSVLDFFA IMGFRCPDRK NIADFLQEVT
SKNDQQQYWY TSTCPYRYVP VERFAEAFRS FRVGKNLSAE LTVPYNREHN HPAALSTTHY
GTKKSELLKA NFSWQLLLMK RNSFIYVFKF IQLLLVALIT MTVFSRTTMH HNSVDDGYIY
LGSLYFAIIM ILFNGFTEVS MLVIRLPVIY KHRDLHFYPA WAYTFPSWLL SIPTSLMESA
MWVAVTYYVI GYDPEISRFL CQFVLLFFLH QMSLALFRVI GSLGRNMIVA NTFGSFAMLV
VMLLGGFIIS KDSIPKWWLW GYWFSPLMYA QNAISVNEFQ GHSWDKKVGK LDNITLGENV
LKLYGLSTQS YWFWIGVGAL FGYTILFNIL FTVFLTYLNP LEQQKAVVSK DKLQEEEKPS
KESNTIELRS YLSGSLAGKN DKEKRGMVLP FQPLSMSFSN VNYYVEMPVE LKKEGVLEDR
LQLLANVTGA FQPGVLTALV GVSGAGKTTL MDVLAGRKTG GFIEGDINIS GYPKNQETFA
RVSGYCEQND IHSPCMTIVE SLLYSAWLRL PSHIKMDTQK AFVKEVMELV ELTQLRGALV
GLPGINGLST EQRKRLTIAV ELVANPSIVF MDEPTSGLDA RSAAIVMRTV RNIVNTGRTI
VCTIHQPSID IFESFDELLL MKRGGELIYA GHLGHNSCKL IEFFEAIDGI PKIKDGYNPA
AWMLEVTSSA TEDQLGVDFA EYYRKSKLFQ QNKELVESLS IPNSDSKNLS FPTKYSQTFF
AQFITCLWKQ NLSYWRNPQY TAVRFFYTII ISVMFGTICW GFGSKRDSQQ DIFNAMGAMY
AAVLFIGITN STSVQPVVSI ERFVSYRERA AGMYSALPLA FSQVAIEFPY VFVQTLVYGT
IFYALASFEW SATKFLWYIF SMYFTLLYFT FFGMMTIAIT PNQVVAPIIA APFYTLWNLF
SGFMIPLRRL PVWWRWYYWA NPISWSLNGL LTSQFGDIDA PMKLADGIHS ISIKIFLKQH
YGFHYERLWF TVSMIAVFCI IFAVVFALAI KFLTFQRR
//
